mall cells lung epidermoid carcinoma in a HTLV1-infected patient: case report and literature revie

Author(s)

Dahy, Flavia Esper ^[1] ; Palhares, Renata Basic ^[1] ; Assone, Tatiane ^{[2, 3]} ; Smid, Jerusa ^[1] ; Luisi de Moura, Joao Victor ^[1] ; Haziot, Michel E. J. ^[1] ; Marcusso, Rosa Maria N. ^[1] ; Penalva de Oliveira, Augusto Cesar ^[1] ; Casseb, Jorge ^{[2, 3]}

Affiliation

^[1] Inst Infectol Emilio Ribas, Ave Angel 2491, 9 Ander, BR-01227200 Sao Paulo, SP - Brazil

^[2] Univ Sao Paulo, Inst Med Trop Sao Paulo, Sao Paulo, SP - Brazil

^[3] Univ Sao Paulo, Fac Med, Lab Invest Med Neurol LIM 56, Sao Paulo, SP - Brazil

• Document type: Review article
• Source: Revista do Instituto de Medicina Tropical de São Paulo; v. 63, 2021.
• Web of Science Citations: 0

Abstract

The human T cell lymphotropic virus type 1 (HTLV-1) is the first human retrovirus discovered. Since then, it has spread worldwide and is mainly associated with adult T cell leukemia/lymphoma (ATLL) and HTLV1-associated myelopathy (HAM). Its relationship, however, with other types of cancer is controversial. We describe the case of a patient presenting with small cells lung epidermoid carcinoma who had recently developed HAM, and a review of the literature related to these conditions. This is the first case of this type of lung cancer, the same of the first description in the literature, associated with HAM outside Japan. (AU)

• FAPESP's process: 14/22827-7 - Prevalence and incidence of early central nervous system disturbance in HTLV-1-infected subjects in Brazil
• Grantee: Jorge Simao do Rosario Casseb
• Support Opportunities: Regular Research Grants