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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Two-step sinter-crystallization of K2O-CaO-P2O5-SiO2 (45S5-K) bioactive glass

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Author(s):
Silva, Lais D. [1, 2] ; Puosso, Fernanda C. [2] ; Soares, Viviane O. [3] ; Filho, Oscar Peitl [2] ; Sabino, Simone do R. F. [4] ; Serbena, Francisco C. [4] ; Crovace, Murilo C. [2] ; Zanotto, Edgar D. [1, 2]
Total Authors: 8
Affiliation:
[1] Univ Fed Sao Carlos, Postgrad Program Mat Sci & Engn, PPG, CEM, BR-13565905 Sao Carlos, SP - Brazil
[2] Fed Univ Sao Carlos UFSCar, Dept Mat Engn DEMa, Ctr Res Technol & Educ Vitreous Mat, CeRTEV, BR-13565905 Sao Carlos, SP - Brazil
[3] State Univ Maringa UEM, Dept Sci, BR-87360000 Goioere, PR - Brazil
[4] State Univ Ponta Grossa UEPG, Dept Phys, BR-84030900 Ponta Grossa, PR - Brazil
Total Affiliations: 4
Document type: Journal article
Source: CERAMICS INTERNATIONAL; v. 47, n. 13, p. 18720-18731, JUL 1 2021.
Web of Science Citations: 0
Abstract

Bioactive glasses and glass-ceramics (GCs) effectively regenerate bone tissue, however most GCs show improved mechanical properties. In this work, we developed and tested a rarely studied bioactive glass composition (24.4K2O-26.9CaO-46.1SiO2-2.6P2O5 mol%, identified as 45S5-K) with different particle sizes and heating rates to obtain a sintered GC that combines good fracture strength, low elastic modulus, and bioactivity. We analyzed the influence of the sintering processing conditions in the elastic modulus, Vickers microhardness, density, and crystal phase formation in the GC. The best GC shows improved properties compared with its parent glass. This glass achieves a good densification degree with a two-step viscous flow sintering approach and the resulting GC shows as high bioactivity as that of the standard 45S5 Bioglass (R). Furthermore, the GC elastic modulus (56 GPa) is relatively low, minimizing stress shielding. Therefore, we unveiled the glass sintering behavior with concurrent crystallization of this complex bioactive glass composition and developed a potential GC for bone regeneration. (AU)

FAPESP's process: 13/07793-6 - CEPIV - Center for Teaching, Research and Innovation in Glass
Grantee:Edgar Dutra Zanotto
Support Opportunities: Research Grants - Research, Innovation and Dissemination Centers - RIDC