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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Effect of Serum Albumin on Porphyrin-Quantum Dot Complex Formation, Characteristics and Spectroscopic Analysis

Full text
Author(s):
Pavanelli, Andre L. S. [1] ; Maximo, Leandro N. C. [2] ; da Silva, Roberto S. [3] ; Borissevitch, Iouri E. [1]
Total Authors: 4
Affiliation:
[1] Univ Sao Paulo, Fac Filosofia Ciencias & Letras Ribeirao Preto, Dept Fis, Av Bandeirantes 3900, BR-14040900 Ribeirao Preto - Brazil
[2] Inst Fed Educ Ciencia & Tecnol Goiano, BR-75790000 Urutai - Brazil
[3] Univ Sao Paulo, Fac Ciencias Farmaceut Ribeirao Preto, Dept Ciencias Biomol, Av Bandeirantes 3900, BR-14040900 Ribeirao Preto - Brazil
Total Affiliations: 3
Document type: Journal article
Source: NANOMATERIALS; v. 11, n. 7 JUL 2021.
Web of Science Citations: 0
Abstract

The effect of bovine serum albumin (BSA) upon interaction between CdTe QD functionalized by 3-Mercaptopropionic Acid (CdTe-3-MPA QD) and two water soluble porphyrins: positively charged meso-tetra methyl pyridyl porphyrin (TMPyP) and negatively charged meso-tetrakis(p-sulfonato-phenyl) porphyrin (TPPS4), was studied in function of pH using the steady-state and time resolved optical absorption and fluorescence spectroscopies. It was shown that, depending on the charge state of the components, interaction with albumin could either prevent the formation of the QD horizontal ellipsis PPh complex, form a mixed QD horizontal ellipsis PPh horizontal ellipsis BSA complex or not affect PPh complexation with QD at all. The obtained results may be of interest for application in photomedicine. (AU)

FAPESP's process: 19/19448-8 - Effect of photobiomodulation as synergistic addendum on photocytotoxicity of ruthenium-phthalocyanine compounds as nitric oxide and singlet oxygen producers: in vitro biochemical evaluation in two- and three-dimensional (3D) tumor cell lines
Grantee:Roberto Santana da Silva
Support Opportunities: Regular Research Grants
FAPESP's process: 16/12707-0 - Cytotoxicity and photo-cytotoxicity of new ruthenium-phthalocyanines compounds as nitric oxide and oxygen singlet producers in cancer cell lines. an innovative purpose for metal based drug
Grantee:Roberto Santana da Silva
Support Opportunities: Regular Research Grants