Follow-up effects of transcranial direct current s... - BV FAPESP
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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Follow-up effects of transcranial direct current stimulation (tDCS) for the major depressive episode: A systematic review and meta-analysis

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Author(s):
Razza, Lais B. [1] ; De Smet, Stefanie [2, 3] ; Moffa, Adriano [4, 5] ; Sudbrack-Oliveira, Pedro [1] ; Vanderhasselt, Marie-Anne [6, 2, 3] ; Brunoni, Andre R. [1, 7]
Total Authors: 6
Affiliation:
[1] Univ Sao Paulo, Fac Med, Serv Interdisciplinar Neuromodulacao, Clin Hosp, Lab Neurociencias LIM27, Dept & Inst Psiquiatria, Sao Paulo - Brazil
[2] Ghent Expt Psychiat GHEP Lab, Ghent - Belgium
[3] Univ Ghent, Ghent Univ Hosp, Dept Head & Skin Psychiat & Med Psychol, Ghent - Belgium
[4] Black Dog Inst, Sydney, NSW - Australia
[5] Univ New South Wales, Sch Psychiat, Sydney, NSW - Australia
[6] Univ Ghent, Dept Expt Clin & Hlth Psychol, Ghent - Belgium
[7] Univ Sao Paulo, Univ Sao Paulo & Hosp Univ, Dept Med Interna, Fac Med, Av Prof Lineu Prestes 2565, BR-05508000 Sao Paulo - Brazil
Total Affiliations: 7
Document type: Review article
Source: PSYCHIATRY RESEARCH; v. 302, AUG 2021.
Web of Science Citations: 0
Abstract

Transcranial Direct Current Stimulation (tDCS) is an effective treatment during the acute phase of a major depressive episode (MDE), although the evidence for its follow-up efficacy is mixed. A systematic review and meta-analysis were performed. MEDLINE/PubMed, Scopus (EMBASE), Web of Science, Cochrane Library and additional sources were searched from inception to April 29, 2021. Studies that followed up adults treated with tDCS during an MDE - using (interventional) and/or not using (observational) tDCS in the follow-up period were included. The primary outcome was the Hedges' g for the follow-up depression scores. Small study effects and sources of heterogeneity were explored. 427 studies were retrieved and 11 trials (13 datasets, n = 311) were included, most presenting moderate bias. Results showed a follow-up depression improvement (k = 13, g = -0.81, 95% confidence interval {[}CI]: -1.28; -0.34, I-2 = 84.0%), which was probably driven by the interventional studies (k = 7, g = -1.12, 95% CI: -1.84; -0.40, I-2 = 87.1%). No predictor of response was associated with the outcome. No risk of publication bias was found. Significant between-study heterogeneity may have influenced the overall results. Our findings suggest that tDCS produces effects beyond the intervention period during MDEs. Maintenance sessions are advised in future research. (AU)

FAPESP's process: 19/06009-6 - Non-implantable neuromodulation therapies: a perspective for the depressed brain
Grantee:Andre Russowsky Brunoni
Support Opportunities: Research Projects - Thematic Grants
FAPESP's process: 19/10760-9 - Circadian variability of motor cortex excitability in patients with Mesial Temporal Lobe Epilepsy: a Transcranial Magnetic Stimulation (TMS) study
Grantee:Pedro Sudbrack Oliveira
Support Opportunities: Scholarships in Brazil - Doctorate
FAPESP's process: 19/07256-7 - Cerebral alteration perfusion induced by transcranial stimulation of the prefrontal cortex: a randomized, placebo-controlled study, using 99mTc SPECT
Grantee:Lais Boralli Razza
Support Opportunities: Scholarships in Brazil - Doctorate (Direct)
FAPESP's process: 18/10861-7 - A Phase-I bilateral project using a sham-controlled, factorial design of transcranial direct current stimulation and theta-burst stimulation to investigate the effects on multimodal assessments of prefrontal cortex functioning
Grantee:Andre Russowsky Brunoni
Support Opportunities: Regular Research Grants