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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

n international collaborative study of 105 new cases of adenomatoid odontogenic tumor

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Author(s):
Oliveira Correa Roza, Ana Luiza [1] ; Carlos, Roman [2] ; van Heerden, Willie F. P. [3] ; Benevenuto de Andrade, Bruno Augusto [4] ; Mosqueda-Taylor, Adalberto [5] ; Santos-Silva, Alan Roger [1] ; Lopes, Marcio Ajudarte [1] ; de Almeida, Oslei Paes [1] ; Romanach, Mario Jose [4] ; Vargas, Pablo Agustin [3, 1]
Total Authors: 10
Affiliation:
[1] Univ Campinas UNICAMP, Piracicaba Dent Sch, Oral Diag Dept, Av Limeira 901, BR-13414903 Sao Paulo - Brazil
[2] Hosp Herrera Llerandi, Ctr Clin Cabeza & Cuello, Pathol Sect, Guatemala City - Guatemala
[3] Univ Pretoria, Sch Dent, Dept Oral Pathol & Oral Biol, Pretoria - South Africa
[4] Fed Univ Rio de Janeiro UFRJ, Sch Dent, Dept Oral Diag & Pathol, Rio De Janeiro - Brazil
[5] Univ Autonoma Metropolitana Xochimilco, Dept Atenc Salud, Mexico City, DF - Mexico
Total Affiliations: 5
Document type: Journal article
Source: ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY; v. 132, n. 3, p. 327-338, SEP 2021.
Web of Science Citations: 1
Abstract

Objective. The aim of this study was to report the clinicopathologic features of 105 new cases of adenomatoid odontogenic tumor (AOT) from Brazil, Guatemala, Mexico, and South Africa. Study Design. Clinical and radiographic data were collected from records of 5 oral pathology laboratories, and all cases were microscopically reviewed. Results. This series of cases included 36 (34.2%) from South Africa; 33 (31.4%) from Brazil; 23 (21.9%) from Mexico; and 13 (12.3%) from Guatemala. Seventy-two patients (68.5%) were females and 33 patients (31.4%) were males, with an average age of 19.2 years. The tumors predominantly affected the anterior maxilla (48.5%), followed by the anterior mandible (29.5%); posterior mandible (15.2%); and posterior maxilla (6.6%). Sixty-three tumors (63.6%) were follicular, 34 (34.3%) were extrafollicular, and 2 (2%) were peripheral. In most cases, the tumors caused considerable cortical expansion (average size 3.4 cm). Microscopically, most cases showed rosette-like and duct-like structures. Conclusions. This is one of the largest case series of AOTs reported in the literature and the first multicenter study involving populations from Latin America and South Africa. In a fifth of the present cases, the posterior regions of the gnathic bones were affected and the tumors demonstrated larger sizes compared with cases occurring in other populations. (AU)

FAPESP's process: 19/02539-0 - Multicentric clinicopathological and proteomic study of adenomatoid odontogenic tumors
Grantee:Ana Luiza Oliveira Corrêa Roza
Support Opportunities: Scholarships in Brazil - Master