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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Hydroxyapatite incorporation into polyamide membrane

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Author(s):
Pontes, Lauany M. [1] ; de Carvalho, Leonardo L. [1] ; Rocha, Lucas A. [1] ; Ferreira, Natalia H. [1] ; Tavares, Denise C. [1] ; Dias, FernandaG G. [1] ; Nassar, Eduardo J. [1] ; da Silva, JorgeV L. [2] ; de Oliveira, Marcelo F. [2] ; Maia, Izaque A. [2]
Total Authors: 10
Affiliation:
[1] Univ Franca, Av Dr Armando Salles Oliveira, 201 Pq Univ, Franca, SP - Brazil
[2] Ctr Tecnol Informacao Renato Archer CTI, Rod Dom Pedro 1, Km 143, 6, BR-13069901 Campinas, SP - Brazil
Total Affiliations: 2
Document type: Journal article
Source: Materials Chemistry and Physics; v. 271, OCT 1 2021.
Web of Science Citations: 0
Abstract

The synthesized hydroxyapaptite (HA) by the precipitation method and incorporated it into polyamide (PA) membrane obtained by additive manufacture. HA formation and incorporation were confirmed by X-ray diffraction, which revealed peaks corresponding to synthetic HA. The infrared spectra displayed the characteristic HA bands between 1093 and 1032 cm(-1), ascribed to phosphate ions (PO43-). After HA incorporation, the membranes were sterilized by using ethylene oxide or an autoclave. Characterization confirmed that HA was present in PA. Cytotoxicity tests did not detect any cytotoxicity for HA, PA, or PA + HA. After incorporation with hydroxyapatite, the membranes were allocated into surgical degrees, sterilized in autoclave and ethylene oxide, and subsequently placed in three distinct intracorporeal sites (subcutaneous tissue close to the right caudal superficial epigastric artery, greater omentum, and tissue surrounding the femur) in rats. None of the rats died during the experiment. After the animals were euthanized, intracorporeal site samples were collected for histological analyses. Neovessels were formed in the proximity of the membranes, and the membranes adhered to the bone. The results indicated that additive manufacturing is important to prepare materials that can be employed in bone implants after these materials undergo appropriate treatment. (AU)

FAPESP's process: 15/20298-0 - Obtention of luminescent LaNbO4:Ln (ln = Dy, TM, er and Yb) matrices prepared by spray pyrolysis process
Grantee:Lucas Alonso Rocha
Support Opportunities: Regular Research Grants
FAPESP's process: 19/02641-0 - 6th Nano Today Conference
Grantee:Eduardo José Nassar
Support Opportunities: Research Grants - Meeting - Abroad
FAPESP's process: 19/26439-5 - Nanoparticles containing lanthanide ions and obtained by the sol-gel methodology for multimodal application in Medicine
Grantee:Eduardo José Nassar
Support Opportunities: Regular Research Grants