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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Pre- and Post-Conditioning of the Heart: An Overview of Cardioprotective Signaling Pathways

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Author(s):
Miranda, Denise Coutinho de [1, 2] ; Faria, Gabriela de Oliveira [1, 2] ; Hermidorff, Milla Marques [1, 2] ; Silva, Fernanda Cacilda dos Santos [2, 3] ; Assis, Leonardo Vinicius Monteiro de [4] ; Isoldi, Mauro Cesar [1]
Total Authors: 6
Affiliation:
[1] Univ Fed Ouro Preto, Inst Exact & Biol Sci, Res Ctr Biol Sci, Cell Signaling Lab, Campus Morro Cruzeiro, BR-35400000 Ouro Preto, MG - Brazil
[2] Univ Fed Ouro Preto, Grad Program Biol Sci CBIOL NUPEB, Ouro Preto - Brazil
[3] Univ Fed Ouro Preto, Inst Exact & Biol Sci, Dept Biol Sci, Lab Cardiovasc Physiol, Ouro Preto - Brazil
[4] Uni Sao Paulo, Inst Biosci, Dept Physiol, Lab Comparat Physiol Pigmentat, Sao Paulo - Brazil
Total Affiliations: 4
Document type: Review article
Source: CURRENT VASCULAR PHARMACOLOGY; v. 19, n. 5, p. 499-524, 2021.
Web of Science Citations: 0
Abstract

Since the discovery of ischemic pre- and post-conditioning, more than 30 years ago, the knowledge about the mechanisms and signaling pathways involved in these processes has significantly increased. In clinical practice, on the other hand, such advancement has yet to be seen. This article provides an overview of ischemic pre-, post-, remote, and pharmacological conditioning related to the heart. In addition, we reviewed the cardioprotective signaling pathways and therapeutic agents involved in the above-mentioned processes, aiming to provide a comprehensive evaluation of the advancements in the field. The advancements made over the last decades cannot be ignored and with the exponential growth in techniques and applications. The future of pre- and post-conditioning is promising. (AU)

FAPESP's process: 18/16511-8 - Involvement of the photosensitive and temporal controlling systems in the development, progression, and metastasis of malignant melanoma: an investigation of novel therapeutic targets
Grantee:Leonardo Vinícius Monteiro de Assis
Support Opportunities: Scholarships in Brazil - Post-Doctoral