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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

From circular synthesis to material manufacturing: advances, challenges, and future steps for using flow chemistry in novel application area

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Author(s):
Sivo, Alessandra [1] ; Galaverna, Renan de Souza [2] ; Gomes, Gustavo Rodrigues [2] ; Pastre, Julio Cezar [2] ; Vile, Gianvito [1]
Total Authors: 5
Affiliation:
[1] Politecn Milan, Dept Chem Mat & Chem Engn Giulio Natta, Piazza Leonardo da Vinci 32, IT-20131 Milan - Italy
[2] Univ Campinas UNICAMP, Inst Chem, POB 6154, BR-13083970 Campinas, SP - Brazil
Total Affiliations: 2
Document type: Review article
Source: REACTION CHEMISTRY & ENGINEERING; v. 6, n. 5, p. 756-786, MAY 1 2021.
Web of Science Citations: 4
Abstract

Continuous-flow technologies are becoming increasingly relevant in the chemistry field. The vast arrays of reactor design, in terms of structural geometry, mixing, and residence time, the modularity of these systems, adaptable for every application, and the easy downstream integrations are at the basis for their success. Over the past decade, the value and potential of flow technologies became apparent, particularly for drug discovery and drug development. However, other areas of research, which include the circular valorization of waste products and the manufacturing of materials and catalysts, have been less touched by the revolution that miniaturization brings in terms of efficiency, safety, environmental impact, and processability. This review critically evaluates the emerging use of flow technologies in these areas, highlighting recent advances, current challenges, and future directions in the quest for leaner and cleaner processing methods. (AU)

FAPESP's process: 14/25770-6 - New frontiers in cross-coupling reactions promoted by palladium: combining enantioselective catalysis, C-H activations, new materials and in flux reactions aiming at high efficiency and sustainability in synthetic processes
Grantee:Carlos Roque Duarte Correia
Support Opportunities: Research Projects - Thematic Grants
FAPESP's process: 14/26378-2 - Development of methodologies and synthetic processes employing a new technological platform: micro and meso reactor assisted synthesis of natural products and derivatives with potential pharmacological activity
Grantee:Júlio Cezar Pastre
Support Opportunities: Research Grants - Young Investigators Grants
FAPESP's process: 18/09861-2 - Synthesis of novel ionic liquids from renewable sources and application on biomass conversion
Grantee:Gustavo Rodrigues Gomes
Support Opportunities: Scholarships in Brazil - Doctorate