Rapid spread of critical priority carbapenemase-producing pathogens in companion animals: a One Health challenge for a post-pandemic world

Author(s)

Sellera, Fabio P. ^{[1, 2]} ; Da Silva, Luciano C. B. A. ^[2] ; Lincopan, Nilton ^{[3, 4]}

Affiliation

^[1] Univ Sao Paulo, Sch Vet Med & Anim Sci, Dept Internal Med, Sao Paulo - Brazil

^[2] Univ Metropolitana Santos, Sch Vet Med, Santos, SP - Brazil

^[3] Univ Sao Paulo, Inst Ciencias Biomed, Dept Microbiol, Sao Paulo - Brazil

^[4] Univ Sao Paulo, Sch Pharm, Dept Clin Anal, Sao Paulo - Brazil

• Document type: Review article
• Source: Journal of Antimicrobial Chemotherapy; v. 76, n. 9, p. 2225-2229, SEP 2021.
• Web of Science Citations: 0

Abstract

The COVID-19 pandemic has increased relationships and interactions between human and companion animals, supported by widespread social distancing and isolation measures. Additionally, the COVID-19 pandemic has Led to an exponential growth in antibiotic and biocide use worldwide, possibly inducing further pressure, contributing to the selection of antibiotic-resistant bacteria, including WHO critical priority pathogens. While data from global surveillance studies reveal a Linear trend of increasing carbapenem resistance among Gram-negative pathogens from companion animals, the acquisition of carbapene-maseproducing Enterobacterales through direct contact with colonized hosts and contaminated veterinary hospital environments has been documented. This article highlights the rapid spread of WHO critical priority carbapenemase-producing pathogens in companion animals, which is a One Health challenge for a post-pandemic world. (AU)

• FAPESP's process: 20/08224-9 - OneBR (One Health Brazilian Resistance): integrated genomic database for surveillance, diagnosis, management and treatment of antimicrobial resistance in the human-animal-environment interface, in Brazil
• Grantee: Nilton Erbet Lincopan Huenuman
• Support Opportunities: Regular Research Grants