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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Dereplication of extracts from nutraceutical mushrooms Pleurotus using molecular network approach

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Author(s):
Caldas, Lhais Araujo [1] ; Zied, Diego Cunha [2] ; Sartorelli, Patricia [1]
Total Authors: 3
Affiliation:
[1] Univ Fed Sao Paulo, Inst Ciencias Ambientais Quim & Farmaceut, Diadema, SP - Brazil
[2] Univ Estadual Paulista, Fac Ciencias Agr & Tecnol, Dracena, SP - Brazil
Total Affiliations: 2
Document type: Journal article
Source: Food Chemistry; v. 370, FEB 15 2022.
Web of Science Citations: 0
Abstract

Pleurotus is an edible mushroom from the well-known genus of Basidiomycetes; it is the second-most commonly consumed mushroom worldwide. This genus is characterized by the presence of steroids, fatty acids, and polysaccharides. Recently, Pleurotus has become popular as a functional food owing to its health benefits, pri-marily because they are a source of vitamins, fibers, minerals, and lipids. In natural products chemistry, der-eplication techniques identify bioactive molecules from natural sources such as plants and fungi without isolating or characterizing molecules. We used dereplication techniques aided by the Global Natural Products Social Molecular Network to analyze the chemical composition of the methanolic extracts of six Pleurotus species (P. sapidus, P. ostreaus, P. ostreaus var. Florida, P. djamor, P. citrinopileatus, and P. pulmonarius), to identify bioactive molecules with nutraceutical properties. Using this technique, we identified several molecular families, including eight fatty acids and seven steroids. Our findings suggest that dereplication is a relatively rapid tool for characterizing fungal species and determining their nutraceutical value. (AU)

FAPESP's process: 16/24985-4 - Study the chemical composition of fungi and plants of the Atlantic Forest aimed at antitumor, antiparasitic and antimicrobial potential
Grantee:Patricia Sartorelli
Support Opportunities: Regular Research Grants
FAPESP's process: 18/21492-2 - Characterization of biomolecules of Agaricus subrufescens in different cultivation conditions
Grantee:Diego Cunha Zied
Support Opportunities: Regular Research Grants
FAPESP's process: 18/25646-4 - Polysaccharides and special metabolites from basidiomycetes fungi: isolation, characterization and evaluation of antitumor potential
Grantee:Lhaís Araújo Caldas
Support Opportunities: Scholarships in Brazil - Doctorate