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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Bioactive Ag3PO4/Polypropylene Composites for Inactivation of SARS-CoV-2 and Other Important Public Health Pathogens

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Ribeiro, Lara K. [1] ; Assis, Marcelo [2, 1] ; Lima, Lais R. [3] ; Coelho, Dyovani [1] ; Goncalves, Mariana O. [4] ; Paiva, Robert S. [3] ; Moraes, Leonardo N. [5, 6] ; Almeida, Lauana F. [5, 6] ; Lipsky, Felipe [7] ; San-Miguel, Miguel A. [7] ; Mascaro, Lucia H. [1] ; Grotto, Rejane M. T. [5, 6] ; Sousa, Cristina P. [4] ; Rosa, V, Ieda L. ; Cruz, Sandra A. [3] ; Andres, Juan [2] ; Longo, Elson [8]
Total Authors: 17
[1] Fed Univ Sao Carlos UFSCar, LIEC, CDMF, BR-13565905 Sao Carlos, SP - Brazil
[2] Univ Jaume I UJI, Dept Phys & Analyt Chem, Castellon de La Plana 12071 - Spain
[3] Fed Univ Sao Carlos UFSCar, Chem Dept, BR-13565905 Sao Paulo, SP - Brazil
[4] Fed Univ Sao Carlos UFSCar, Biomol & Microbiol Lab LaMiB, Biotechnol Grad Program, BR-13565905 Sao Carlos, SP - Brazil
[5] Sao Paulo State Univ UNESP, Sch Agr, BR-18610034 Botucatu, SP - Brazil
[6] Sao Paulo State Univ Unesp, Clin Hosp Botucatu, Med Sch, Mol Lab, BR-18618687 Botucatu, SP - Brazil
[7] State Univ Campinas UNICAMP, Inst Chem, BR-13083970 Campinas, SP - Brazil
[8] Rosa, Ieda L., V, Fed Univ Sao Carlos UFSCar, LIEC, CDMF, BR-13565905 Sao Carlos, SP - Brazil
Total Affiliations: 8
Document type: Journal article
Source: Journal of Physical Chemistry B; v. 125, n. 38, p. 10866-10875, SEP 30 2021.
Web of Science Citations: 0

The current unprecedented coronavirus pandemic (COVID-19) is increasingly demanding advanced materials and new technologies to protect us and inactivate SARS-CoV-2. In this research work, we report the manufacture of Ag3PO4(AP)/polypropylene (PP) composites using a simple method and also reveal their long-term anti-SARS-CoV-2 activity. This composite shows superior antibacterial (against Staphylococcus aureus and Escherichia coli) and antifungal activity (against Candida albicans), thus having potential for a variety of technological applications. The as-manufactured materials were characterized by XRD, Raman spectroscopy, FTIR spectroscopy, AFM, UV-vis spectroscopy, rheology, SEM, and contact angle to confirm their structural integrity. Based on the results of first-principles calculations at the density functional level, a plausible reaction mechanism for the initial events associated with the generation of both hydroxyl radical (OH)-O-center dot and superoxide radical anion O-center dot(2)- in the most reactive (110) surface of AP was proposed. AP/PP composites proved to be an attractive avenue to provide human beings with a broad spectrum of biocide activity. (AU)

FAPESP's process: 13/07296-2 - CDMF - Center for the Development of Functional Materials
Grantee:Elson Longo da Silva
Support Opportunities: Research Grants - Research, Innovation and Dissemination Centers - RIDC
FAPESP's process: 16/23891-6 - Computer modeling of condensed matter
Grantee:Alex Antonelli
Support Opportunities: Research Projects - Thematic Grants
FAPESP's process: 17/11986-5 - Generation and storage of New Energy: bringing technological development for the country
Grantee:Ana Flávia Nogueira
Support Opportunities: Research Grants - Research Centers in Engineering Program
FAPESP's process: 16/13423-5 - Compounds produced by endophyte microorganisms isolated from Brazilian tropical savannah: bioactivity, association with a-Ag2WO4 and biotechnological applications
Grantee:Cristina Paiva de Sousa
Support Opportunities: Regular Research Grants
FAPESP's process: 17/26105-4 - Multi-user equipment approved in grant 2016/23891-6 high performace computational cluster
Grantee:Alex Antonelli
Support Opportunities: Multi-user Equipment Program
FAPESP's process: 17/07711-0 - Detection of ZIKA Virus (ZIKV), after in vitro exposition, in the Peripheral Blood Mononuclear Cells and Platelets from non-infected individuals: Influence of the Genetic Polymorphisms
Grantee:Rejane Maria Tommasini Grotto
Support Opportunities: Regular Research Grants