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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

The influence of the ACTN3 R577X polymorphism in the responsiveness to post-activation jump performance enhancement in untrained young men

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Author(s):
Guilherme Beneduzzi Mantovani [1] ; Renan Vieira Barreto [2] ; Victor Alvino de Souza [3] ; Carlos Roberto Bueno Júnior [4] ; Claudio de Oliveira Assumpção [5] ; Camila Coelho Greco [6] ; Benedito Sérgio Denadai [7] ; Leonardo Coelho Rabello de Lima
Total Authors: 8
Affiliation:
[1] São Paulo State University. Department of Physical Education. Human Performance Laboratory - Brasil
[2] São Paulo State University. Department of Physical Education. Human Performance Laboratory - Brasil
[3] São Paulo State University. Department of Physical Education. Human Performance Laboratory - Brasil
[4] University of São Paulo. School of Physical Education and Sport of Ribeirão Preto - Brasil
[5] Federal University of Ceará. Institute of Physical Education and Sports. Biodynamics Research Group of Human Movement - Brasil
[6] São Paulo State University. Department of Physical Education. Human Performance Laboratory - Brasil
[7] São Paulo State University. Department of Physical Education. Human Performance Laboratory - Brasil
Total Affiliations: 8
Document type: Journal article
Source: Rev. bras. cineantropom. desempenho hum.; v. 23, 2021-09-24.
Abstract

ABSTRACT We aimed to investigate the influence of alpha-actinin-3 (ACTN3) R577X polymorphism on responsiveness to post-activation performance enhancement (PAPE) of countermovement jumps (CMJ) in untrained subjects. Sixteen untrained men were allocated into two groups according to their ACTN3 gene alleles: homozygous for the X allele (XX, n = 9) or homozygous for the R allele (RR, n = 7). CMJ height, mean power output and vertical force were determined twice (CMJ1 and CMJ2) in two conditions: control (CON) and potentiated (PAPE). In the CON condition, CMJ were performed before and after a 15-min rest. In the PAPE condition, CMJ were performed 15 min before and 4 min following five squats with a 5-repetition maximum (5RM) load. Different conditions were applied on separate days in a randomized order. Statistical analysis involved three-way ANOVAs to compare the differences between conditions (CON and PAPE), time (CMJ1 and CMJ2), and groups (XX and RR). Significance level considered was p < 0.05. Effect sizes were calculated as Cohen’s d. The effect sizes for changes in CMJ height for CON and following pre-activation for PAPE were 0.04 and 0.08, respectively. No significant differences were found for CMJ height between XX and RR at baseline (1.07 ± 2.54 cm e -0.82 ± 2.56 cm, respectively). No differences were found (p>0.05) in responsiveness to PAPE between the groups (XX = -0.20 ± 1.6 cm and RR = -0.81 ± 2.7 cm). We conclude that ACTN3 gene polymorphisms does not influence responsiveness to PAPE. (AU)

FAPESP's process: 18/05336-0 - The influence of the ACTN3 gene polymorphism in the responsiveness to the post-activation potentiation
Grantee:Guilherme Beneduzzi Mantovani
Support Opportunities: Scholarships in Brazil - Scientific Initiation
FAPESP's process: 19/00511-1 - The effect of different warm-up protocols on post-activation potentiation in high level trained athletes
Grantee:Guilherme Beneduzzi Mantovani
Support Opportunities: Scholarships abroad - Research Internship - Scientific Initiation