| Full text | |
| Author(s): |
Patricia Capellato
[1]
;
Lucas V. B. Vasconcelos
[2]
;
Filipe B. Vilela
[3]
;
Gilza Carla Ribeiro
[4]
;
Cristiane A. P. Correia
[5]
;
Gilbert Silva
[6]
;
Daniela Sachs
[7]
;
André L. R. Rangel
[8]
;
Cecilia A. de C. Zavaglia
[9]
;
Ana P. R. Alves Claro
[10]
Total Authors: 10
|
| Affiliation: | [1] Universidade Federal de Itajubá. Instituto de Física e Química - Brasil
[2] Universidade Federal de Itajubá. Instituto de Física e Química - Brasil
[3] Universidade Federal de Itajubá. Instituto de Física e Química - Brasil
[4] Universidade Federal de Itajubá. Instituto de Física e Química - Brasil
[5] Universidade Estadual Paulista "Júlio de Mesquita Filho". Departamento de Bioquímica - Brasil
[6] Universidade Federal de Itajubá. Instituto de Engenharia Mecânica - Brasil
[7] Universidade Federal de Itajubá. Instituto de Física e Química - Brasil
[8] Universidade Estadual Paulista. Departamento de Materiais e Tecnologia. Escola de Engenharia - Brasil
[9] Universidade Estadual de Campinas. Faculdade de Engenharia Mecânica - Brasil
[10] Universidade Estadual Paulista. Departamento de Materiais e Tecnologia. Escola de Engenharia - Brasil
Total Affiliations: 10
|
| Document type: | Journal article |
| Source: | MATERIALS RESEARCH-IBERO-AMERICAN JOURNAL OF MATERIALS; v. 24, n. 6 2021-10-27. |
| Abstract | |
Abstract One of the major health security challenges of the 21st century is the occurrence of microbial infections and bacterial complications that could affect 10 million people by 2050. On the biomaterial field, implant metallic currently replaces partial or total body parts and can fail to be integrated into the body due to infections. This study performs two combined surface modifications on Ti-30Ta alloy, in order to obtain an infection-resistance and osseointegration surface on metallic implants to be tested within bacterial biofilm. The Group 1 investigated surface modifications by the anodization process in the electrolyte glycerol + NH4F 0.25% at 30V- 9 hours and annealed in 530°C (5°C/min). The Group 2 underwent the same process as Group 1 and, additionally, the samples were immersed in 0.3 M CaCl2 and 0.5 M Na2HPO4 solutions for hydroxyapatite growth. The substrate was characterized using scanning electron microscopy (SEM), X-ray diffractometer (XRD) and dynamic contact angle. S. epidermidis bacterial adhesion and biofilm formation. The results indicated that the Group 1 shows a higher antimicrobial activity, hydrophilic behavior and potential to be used for metallic implant applications. The Group 2 with the hydroxyapatite film coating did not have an improvement in the antimicrobial response. (AU) | |
| FAPESP's process: | 14/14533-3 - Evaluation of PCL electrospun fibers on the Ti-30Ta alloy surface after TiO2 nanotubes growth |
| Grantee: | Patricia Capellato |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |