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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Overview of chitosan-based nanosystems for prostate cancer therapy

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de Araujo, Jennifer Thayanne Cavalcante [1] ; Tavares Junior, Alberto Gomes [1] ; Di Filippo, Leonardo Delello [1] ; Duarte, Jonatas Lobato [1] ; Ribeiro, Tais de Cassia [1] ; Chorilli, Marlus [1]
Total Authors: 6
[1] Sao Paulo State Univ UNESP, Sch Pharmaceut Sci, BR-14800903 Araraquara, SP - Brazil
Total Affiliations: 1
Document type: Journal article
Source: EUROPEAN POLYMER JOURNAL; v. 160, NOV 5 2021.
Web of Science Citations: 0

Prostate cancer is considered a non-cutaneous cancer and has high prevalence and mortality rates worldwide. Chemotherapeutic agents have several side effects due to non-specific systemic biodistribution. Alternatively, nanocarriers can be an interesting strategy to overcome the limitations and undesirable consequences of conventional treatments. This review aims to explore the properties of chitosan, as well as its pharmaceutical applications in drug delivery nanosystems as a carrier or as a surface moiety for prostate cancer-targeted treatment. The chitosan-based polymeric nanosystems demonstrated good results regarding the delivery of anticancer drugs, improving their release, reducing toxicity, and promoting specific delivery to the tumor cells of prostate cancer. (AU)

FAPESP's process: 19/19228-8 - Evaluation of curcumin potential incorporated in mesoporous silica nanoparticles dispersed in thermo-responsive hydrogels in the treatment of Alzheimer's Disease
Grantee:Tais de Cassia Ribeiro
Support Opportunities: Scholarships in Brazil - Master
FAPESP's process: 19/25125-7 - Nanoemulsions containing terpenes as potentials larvicides and repellents against Aedes aegypti (Linnaeus, 1762)
Grantee:Jonatas Lobato Duarte
Support Opportunities: Scholarships in Brazil - Doctorate
FAPESP's process: 18/18488-3 - Potential evaluation of nanostructured lipid carriers functionalized with bevacizumab for delivery of docetaxel in the treatment of glioblastoma
Grantee:Leonardo Delello Di Filippo
Support Opportunities: Scholarships in Brazil - Master
FAPESP's process: 20/06212-3 - Evaluation of the potential of curcumin encapsulated polymeric nanoparticles associated with D-±-tocopheryl polyethylene glycol 1000 succinate functionalized with bevacizumab in the treatment of Prostate Cancer
Grantee:Jennifer Thayanne Cavalcante de Araújo
Support Opportunities: Scholarships in Brazil - Doctorate