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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Lycopene: From tomato to its nutraceutical use and its association with nanotechnology

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Carvalho, Gabriela Correa [1] ; Furquim de Camargo, Bruna Almeida [1] ; Cavalcante de Araujo, Jennifer Thayanne [1] ; Chorilli, Marlus [1]
Total Authors: 4
[1] Sao Paulo State Univ, Sch Pharmaceut Sci, UNESP, BR-14800903 Araraquara, SP - Brazil
Total Affiliations: 1
Document type: Journal article
Source: TRENDS IN FOOD SCIENCE & TECHNOLOGY; v. 118, p. 447-458, DEC 2021.
Web of Science Citations: 1

Background: Lycopene, a red-colored carotenoid, has several biological properties, such as antioxidant, cardioprotective, antihypercholesterolemic, antidiabetic, antimicrobial, photoprotector and anticancer, making desirable its use as nutraceutical. Despite the fact that it can be found in several foods, tomato deserves great prominence because it is the major extraction source and the cheapest raw material, being therefore the human most ingested source. Tomato also stands out for being the source where lycopene was first discovered. Scope and approach: This review article seeks to highlight the entire route that lycopene passes until its use as a nutraceutical, highlighting the main methods of extraction, concentration and quantification. Key findings and conclusions: Solvent extraction and super-critical fluid extraction, centrifugation and evaporation and HPLC and UV-vis spectrophotometer were the researchers most chosen methods of extraction, concentration and quantification, respectively. It also was noted that its association with nanotechnology is desirable to circumvent limitations related to its physicochemical characteristics that limit, not only its extraction process but also its nutraceutical use. (AU)

FAPESP's process: 19/26821-7 - Nano-in-nano containing curcumin and benzydamine hydrochloride for the treatment of Vulvovaginal Candidiasis: from development to biological application in vitro and in vivo
Grantee:Gabriela Corrêa Carvalho
Support Opportunities: Scholarships in Brazil - Doctorate
FAPESP's process: 20/06212-3 - Evaluation of the potential of curcumin encapsulated polymeric nanoparticles associated with D-±-tocopheryl polyethylene glycol 1000 succinate functionalized with bevacizumab in the treatment of Prostate Cancer
Grantee:Jennifer Thayanne Cavalcante de Araújo
Support Opportunities: Scholarships in Brazil - Doctorate