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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Effect of the protein structure and heme iron coordination sphere on the long-range electron transfer from hematite and zinc oxide nanostructures to cytochrome c

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Author(s):
Menezes, Lucivaldo R. [1] ; Araujo-Chaves, Juliana C. [1] ; Lopes, David M. [1] ; Bronzato, Julia D. [1] ; Sombrio, Guilherme [1] ; Criado, Denise [1] ; Zuniga, Alejandro [2] ; Lanfredi, Alexandre J. C. [2] ; Souza, Jose A. [1] ; Nantes-Cardoso, Iseli L. [1]
Total Authors: 10
Affiliation:
[1] Fed Univ ABC, Ctr Nat Sci & Humanities, BR-09210580 Santo Andre, SP - Brazil
[2] Fed Univ ABC, Ctr Engn & Appl Social Sci, BR-09210580 Santo Andre, SP - Brazil
Total Affiliations: 2
Document type: Journal article
Source: International Journal of Nanotechnology; v. 17, n. 1, SI, p. 42-56, 2020.
Web of Science Citations: 2
Abstract

Cytochrome c has gained increasing interest in non-biological areas because of its electronic and magnetic properties that are applicable in spintronics and energy. The chiral helicoidal structure of cytochrome c gives to this protein the property of chiral-induced spin selectivity (CISS) applicable to spintronics and energy. In a previous study, it was demonstrated that Fe2O3, structured as layers of nanowires (NWs) and nanoflakes (NFs), contrary to ZnONWs, can efficiently reduce cytochrome c heme when submitted to illumination with a sunlight simulator. The present study investigated the influence of alpha-helix content and heme iron axial ligands on the capacity of cytochrome c to accept electrons from Fe(2)O(3)NWs (NFs) pristine and decorated with gold nanoparticles. Microperoxidase-11 (MP-11), a heme-undecapeptide produced by cytochrome c digestion was irradiated in the presence of Fe(2)O(3)NFs. Efficient photoreduction was observed only for MP-11 with hexacoordinated heme iron. The results demonstrated that the heme coordination sphere rather than the alpha-helix content is crucial for the efficient long-range electron transfer from hematite to heme iron. Also, ZnO grown as nanoflowers (NFws) at room temperature was tested as a photoreduction agent, and like ZnONWs was also an inefficient photoreduction agent for cytochrome c. (AU)

FAPESP's process: 17/02317-2 - Interfaces in materials: electronic, magnetic, structural and transport properties
Grantee:Adalberto Fazzio
Support Opportunities: Research Projects - Thematic Grants