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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

revalence of Leishmania infantum in Dogs from Deforested Areas of the Amazon Biom

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Author(s):
Campolongo, Caio [1] ; Silva, Ryan Emiliano da [2] ; Azevedo, Roberta Carvalho de Freitas e [1] ; Pesenato, Isabella Pereira [2] ; Carioca, Ana Carolina Fernandes [1] ; Alves, Bruna Farias [2] ; Castelli, Giovanna Stefani Nosberto [1] ; Onofrio, Valeria Castilho [1, 3] ; Marcili, Arlei [1, 2]
Total Authors: 9
Affiliation:
[1] Univ Santo Amaro, Posgrad Program Anim Med Welf & One Hlth, Av Prof Eneas Siqueira Neto, BR-04829300 Sao Paulo, SP - Brazil
[2] Univ Sao Paulo, Sch Vet Med & Anim Sci, Dept Prevent Vet Med & Anim Hlth, Lab Parasit Dis, Sao Paulo, SP - Brazil
[3] Butantan Inst, Lab Zool Collect, Sao Paulo, SP - Brazil
Total Affiliations: 3
Document type: Journal article
Source: VECTOR-BORNE AND ZOONOTIC DISEASES; DEC 2021.
Web of Science Citations: 0
Abstract

Background and Objectives: Species of Leishmania genus are intracellular parasites responsible for severe zoonotic diseases worldwide, such as leishmaniasis. In Brazil, the most important species is Leishmania infantum. In the northern region, the state of Para is notable, with a high number of cases reported in recent years. The second largest number of cases of human visceral leishmaniasis in the region in recent years has been reported in the city of Maraba (Para state). We investigated the prevalence of L. infantum in domestic dogs from Maraba in Amazon region in Brazil.Materials and Methods: A total of 400 blood samples were tested using the dual-path platform chromatographic immunoassay (DPP(R) CVL-Bio-Manguinhos), and molecular diagnosis based in cathepsin L-like gene, which has better specificity and sensitivity than other similar tests.Results: The prevalence of L. infantum was 75.5% (302/400) in the serological test, and 59.25% (237/400) in molecular diagnosis, and 45.5% (182/400) in both tests.Interpretation and Conclusion: The results confirmed that the parasite L. infantum was prevalent in the dog population of the studied region and adoption of appropriate public policies are urgently needed. (AU)

FAPESP's process: 15/25592-3 - Taxonomy and phylogeny of Trypanosoma species: description of a new species from wild animals
Grantee:Arlei Marcili
Support Opportunities: Regular Research Grants