Selective C-C Bond Cleavage Strategy Promoted by Visible Ligh

Gallo, Rafael D. C.; Duarte, Marcelo; da Silva, Amanda F.; Okada, Jr., Celso Y.; Deflon, Victor M.; Jurberg, Igor D.

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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Selective C-C Bond Cleavage Strategy Promoted by Visible Ligh

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Author(s):	Gallo, Rafael D. C. ^[1] ; Duarte, Marcelo ^[1] ; da Silva, Amanda F. ^[1] ; Okada, Jr., Celso Y. ^[1] ; Deflon, Victor M. ^[2] ; Jurberg, Igor D. ^[1] Total Authors: 6
Affiliation:	^[1] Univ Estadual Campinas, Inst Chem, BR-13083862 Campinas - Brazil ^[2] Univ Sao Paulo, Inst Chem Sao Carlos, BR-13566590 Sao Carlos, SP - Brazil Total Affiliations: 2
Document type:	Journal article
Source:	ORGANIC LETTERS; v. 23, n. 22, p. 8916-8920, NOV 19 2021.
Web of Science Citations:	1
Abstract
A new visible-light-promoted reaction between aryldiazoacetates and 1,3-diketones allows good yields and selectivities for C-C bond insertions, leading to the corresponding 1,4-dicarbonyl compounds. This transformation is straightforward and highly practical. It tolerates air and moisture and does not require the use of any metals. Mechanistic investigations support the involvement of a key cyclopropanol intermediate derived from an intramolecular rearrangement. (AU)

FAPESP's process:	20/00144-6 - Structural proteomics: design, synthesis and application of new generation crosslinking agents
Grantee:	Rafael Douglas Clemente Gallo
Support Opportunities:	Scholarships in Brazil - Post-Doctoral


FAPESP's process:	19/01235-8 - Photochemistry with visible light using donor-acceptor diazocompounds
Grantee:	Igor Dias Jurberg
Support Opportunities:	Regular Research Grants

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