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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

ccuracy of radiographic pixel linear analysis in detecting bone loss in periodontal disease: Study in diabetic rat

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Author(s):
Emerenciano Bueno, Carlos Roberto [1, 2] ; Sumida, Doris Hissako [3] ; Hungaro Duarte, Marco Antonio [4] ; Ordinola-Zapata, Ronald [5] ; Azuma, Mariane Maffei [6, 1] ; Guimaraes, Gustav [7] ; Pinheiro, Tiago Novaes [8] ; Angelo Cintra, Luciano Tavares [1, 9]
Total Authors: 8
Affiliation:
[1] Sao Paulo State Univ Unesp, Sch Dent, Dept Prevent & Restorat Dent, Endodont Sect, Sao Paulo, SP - Brazil
[2] State Univ Northern Parana UENP, Sch Dent, Dept Endodont, Jacarezinho, PR - Brazil
[3] Sao Paulo State Univ Unesp, Sch Dent, Dept Basic Sci, Sao Paulo, SP - Brazil
[4] Univ Sao Paulo, Sch Dent, Dept Dent Endodont & Dent Mat, Bauru, SP - Brazil
[5] Univ Minnesota, Sch Dent, Div Endodont, Minneapolis, MN 55455 - USA
[6] Univ Michigan, Dept Cariol Restorat Sci & Endodont, Ann Arbor, MI 48109 - USA
[7] Univ Ctr Sao Lucas, Sch Dent, Dept Periodont, Porto Velho, RO - Brazil
[8] Amazonas State Univ, Dept Oral Pathol & Oral Med, Dent Sch, Manaus, Amazonas - Brazil
[9] Sao Paulo State Univ Unesp, Sch Dent, Dent Assistance Ctr Disabled Persons CAOE, Aracatuba, SP - Brazil
Total Affiliations: 9
Document type: Journal article
Source: SAUDI DENTAL JOURNAL; v. 33, n. 8, p. 987-996, DEC 2021.
Web of Science Citations: 0
Abstract

Introduction: Periodontitis, a complex infectious disease that may lead to irreversible loss of periodontium, is considered a predisposing agent for developing insulin resistance due to the release of inflammatory mediators, showing a bilateral relationship with diabetes mellitus. The investigation of periodontal disease requires a clinical approach and complete intraoral radiographs, even with increasing concerns about radiation exposure. Thus, this study assesses pixel linear analysis accuracy using digital radiography via Digora (R) in detecting alveolar bone destruction in diabetic rats with periodontal disease. Methodology: 40 rats were divided into groups (n = 10): control (C), rats with periodontal disease (PD), experimental diabetic rats (ED), experimental diabetic rats with periodontal disease (ED-PD). Diabetes was induced by streptozotocin and periodontal disease by periodontal ligature. After 30 days, maxillae bone destruction was obtained by linear analysis of vertical bone loss using digital radiography and then assessed by micro-CT and histology. Data were analyzed by ANOVA and Tukey's test (p < 0.05). Results: Radiographic, micro-CT and histological analysis presented accurate and similar results. PD and ED-PD groups showed higher bone destruction than C and ED groups (p < 0.05). Moreover, the ED-PD group had higher bone loss than the PD group (p < 0.05). Conclusion: The pixel linear analysis via digital radiography was an accurate, low-cost alternative in detecting alveolar bone loss in this rat model. Micro-CT and histological analysis may also be used to obtain linear measures to assess and compare periodontal bone destruction in diabetic rats. (C) 2021 The Authors. Production and hosting by Elsevier B.V. on behalf of King Saud University. (AU)

FAPESP's process: 10/16999-9 - Effect of diabetes on the development of pulp infection and/or periodontal disease. Histological study in rats.
Grantee:Annelise Katrine Carrara Prieto
Support Opportunities: Scholarships in Brazil - Scientific Initiation
FAPESP's process: 11/11337-0 - Effect of diabetes on the induction and progression of pulp and periodontal infections. Analysis by digital images.
Grantee:Clicia Pereira Ribeiro
Support Opportunities: Scholarships in Brazil - Scientific Initiation