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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

CHEMISTRY BEHIND DRUGS DISTRIBUTED BY THE POPULAR PHARMACY PROGRAM IN BRAZIL: SYNTHETIC ROUTES, STRUCTURE-ACTIVITY RELATIONSHIP AND FUTURE PERSPECTIVES

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Author(s):
Giovanny C. dos Santos [1] ; Julia L. Rodrigues [2] ; Júllia R. de Souza [3] ; Luiz C. da Silva-Filho [4] ; Bruno H. S. T. da Silva [5]
Total Authors: 5
Affiliation:
[1] Universidade Estadual Paulista. Departamento de Química - Brasil
[2] Universidade Estadual Paulista. Departamento de Química - Brasil
[3] Universidade Federal de Uberlandia. Instituto de Química - Brasil
[4] Universidade Estadual Paulista. Departamento de Química - Brasil
[5] Universidade Federal de Uberlandia. Instituto de Química - Brasil
Total Affiliations: 5
Document type: Journal article
Source: Química Nova; v. 44, n. 10, p. 1280-1299, 2021-12-20.
Abstract

Certainly, most chemistry students, patients or simply curious, have already questioned themselves about certain medications present in their daily lives, trying to understand how they work and even how they can be obtained. Based on that, this work presents some known synthetic routes and the structure-activity relationship (SAR), of some active pharmaceutical ingredients present in medications distributed in Brazil by the government program known as “Farmacia Popular”, emphasizing the functional groups and chemical structure linked to their mechanisms of action. Some other characteristics and future perspectives of such drugs and their respective active principles are also highlighted. (AU)

FAPESP's process: 18/14506-7 - Study about the one-pot synthesis and application as organic dyes of quinolone and anthrazoline derivatives
Grantee:Luiz Carlos da Silva Filho
Support type: Regular Research Grants
FAPESP's process: 18/10112-4 - "Studies on the synthesis and photochemical and photophysical characterization of quinoline derivatives with donor-Pi-acceptor structure for use as sensitizing dyes of organic electronic devices"
Grantee:Giovanny Carvalho dos Santos
Support type: Scholarships abroad - Research Internship - Doctorate
FAPESP's process: 15/00615-0 - Studies on the synthesis and photochemical and photophysical characterization of quinoline derivatives with donor-p-acceptor structure for use as sensitizing dyes in organic electronic devices
Grantee:Giovanny Carvalho dos Santos
Support type: Scholarships in Brazil - Doctorate