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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Ultrasonography of the nuchal translucency of healthy and abnormal English Bulldog fetuses

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Author(s):
Letícia Pavan [1] ; Beatriz Gasser [2] ; Marjury Cristina Maronezi [3] ; Igor Cezar Kniphoff da Cruz [4] ; Rafael Kretzer Carneiro [5] ; Priscila Silva [6] ; Ricardo Andrés Ramirez Uscategui [7] ; Luciana Cristina Padilha-Nakaghi [8] ; Marcus Antônio Rossi Feliciano
Total Authors: 9
Affiliation:
[1] Universidade Estadual Paulista. Departamento de Reprodução Animal - Brasil
[2] Universidade Estadual Paulista. Departamento de Reprodução Animal - Brasil
[3] Universidade Estadual Paulista. Departamento de Reprodução Animal - Brasil
[4] Universidade Estadual Paulista. Departamento de Reprodução Animal - Brasil
[5] Universidade Estadual Paulista. Departamento de Reprodução Animal - Brasil
[6] Universidade Estadual Paulista. Departamento de Reprodução Animal - Brasil
[7] Universidade Federal do Vales do Jequitinhonha e Mucuri - Brasil
[8] Universidade Estadual Paulista. Departamento de Reprodução Animal - Brasil
Total Affiliations: 9
Document type: Journal article
Source: Animal Reproduction; v. 18, n. 4 2021-12-10.
Abstract

Abstract The aim of this study was to measure the nuchal translucency (NT) of canine fetuses to establish reference values ​​for healthy gestational processes and to verify its effectiveness in the diagnosis of congenital abnormalities. On day 34 of gestation, the NT of three fetuses from each of the 26 English bulldog female dogs was measured. The first fetus was the one located immediately cranial to the bladder, the second was selected from the left side of the abdomen, and the third from the right side. The reference values for healthy animals were offset using descriptive statistics. The diagnostic ability of the test to identify fetal malformations was studied using receiver operating characteristic curve analysis. Of the 26 litters, only 18 had healthy fetuses, 4 had fetuses with anasarca, 3 had fetuses with abdominal wall defects, and 1 had both types of abnormalities. The NT was higher in canine fetuses that presented anasarca in the litter than in normal litters (1.8 ± 0.77 mm vs. 1.4 ± 0.48 mm; P = 0.0249), with a cut-off value of NT > 1.45 mm (sensitivity = 61.54%, specificity = 70.18%). NT greater than 1.45 mm seems to be a diagnostic tool for the identification of anasarca during gestation of bulldogs. Considering the unprecedented use of this parameter in canine species and the limitations found during the study, further studies will be needed in order to use it on clinical practice. (AU)

FAPESP's process: 17/14957-6 - Study of new biotechnics for reproduction of canine and small ruminants
Grantee:Wilter Ricardo Russiano Vicente
Support Opportunities: Research Projects - Thematic Grants
FAPESP's process: 19/15282-8 - MUE granted in the process 17/14957-6: Siemens S2000
Grantee:Wilter Ricardo Russiano Vicente
Support Opportunities: Multi-user Equipment Program