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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Deficiency and Insufficiency of Vitamin D in Women of Childbearing Age: A Systematic Review and Meta-analysis

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Author(s):
Rosa Camila Lucchetta [1] ; Isabele Held Lemos [2] ; Ana Luísa Rodriguez Gini [3] ; Sophia de Andrade Cavicchioli [4] ; Marcela Forgerini [5] ; Fabiana Rossi Varallo [6] ; Mariane Nunes de Nadai [7] ; Fernando Fernandez-Llimos [8] ; Patricia de Carvalho Mastroianni [9]
Total Authors: 9
Affiliation:
[1] Universidade Estadual de São Paulo. School of Pharmaceutical Sciences. Department of Drugs and Medicines - Brasil
[2] Universidade Estadual de São Paulo. School of Pharmaceutical Sciences. Department of Drugs and Medicines - Brasil
[3] Universidade Estadual de São Paulo. School of Pharmaceutical Sciences. Department of Drugs and Medicines - Brasil
[4] Universidade de Araraquara - Brasil
[5] Universidade Estadual de São Paulo. School of Pharmaceutical Sciences. Department of Drugs and Medicines - Brasil
[6] Universidade de São Paulo. Faculty of Pharmaceutical Sciences of Ribeirão Preto. Department of Pharmaceutical Sciences - Brasil
[7] Universidade de São Paulo. Bauru School of Dentistry. Department of Dentistry, Pediatric Dentistry and Public Health - Brasil
[8] Universidade do Porto. Faculty of Pharmacy. Laboratory of Pharmacology - Portugal
[9] Universidade Estadual de São Paulo. School of Pharmaceutical Sciences. Department of Drugs and Medicines - Brasil
Total Affiliations: 9
Document type: Journal article
Source: Revista Brasileira de Ginecologia e Obstetrícia; v. 44, n. 4, p. 409-424, 2022-06-27.
Abstract

Abstract Objective To estimate the prevalence of inadequate vitamin D level and its associated factors for women of childbearing age in Brazil. Methods A systematic reviewwas conducted (last updatedMay 2020).Meta-analyses were performed using the inverse-variance for fixed models with summary proportion calculation by Freeman-Tukey double arcsine. Reporting and methodological quality were assessed using the Joanna Briggs Institute tool for prevalence studies. Results Our review identified 31 studies, comprising 4,006 participants. All the studies had at least one weakness, mainly due to the use of convenience sampling and small sample size. The overall prevalence of vitamin D deficiency, insufficiency, and both deficiency and insufficiency were 35% (confidence interval, 95%CI: 34-37%), 42% (95%CI: 41-44%), and 72% (95%CI: 71-74%), respectively. Conclusion Although the magnitude of the prevalence of inadequate levels of vitamin D is uncertain, the evidence suggests that presence of vitamin D deficiency or insufficiency in women of reproductive age can cause moderate to severe problems. (AU)

FAPESP's process: 18/07501-9 - Genetic determinants of gastrointestinal bleeding associated with the use of ASA as an antiplalet agent: a case-control study
Grantee:Marcela Forgerini
Support Opportunities: Scholarships in Brazil - Doctorate (Direct)