Hyperkalemia in Diabetes Mellitus Setting

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Author(s):	Goia-Nishide, Kleber ; Coregliano-Ring, Lucas ; Bevilaqua Rangel, Erika Total Authors: 3
Document type:	Journal article
Source:	DISEASES; v. 10, n. 2, p. 17-pg., 2022-06-01.
Abstract
Diabetes mellitus is a global health problem that affects 9.3% of the worldwide population and is associated with a series of comorbidities such as heart failure (HF) and chronic kidney disease (CKD). Diabetic patients, especially those with associated CKD, are more susceptible to present potassium disorders, in particular hyperkalemia due to kidney disease progression or use of renin-angiotensin-aldosterone blockers. Hyperkalemia is a potentially life-threatening condition that increases the risk of cardiac arrhythmia episodes and sudden death, making the management of potassium levels a challenge to reduce the mortality rate in this population. This review aims to briefly present the potassium physiology and discuss the main conditions that lead to hyperkalemia in diabetic individuals, the main signs, symptoms, and exams for the diagnosis of hyperkalemia, and the steps that should be followed to manage patients with this potentially life-threatening condition. (AU)

FAPESP's process:	21/02216-7 - Combined treatment with empagliflozin, caloric restriction, mesenchymal stem cells and Klotho for halting the progression of diabetic kidney disease and ameliorate acute kidney injury
Grantee:	Érika Bevilaqua Rangel
Support Opportunities:	Regular Research Grants