Combined effects of polyethylene spiked with the antimicrobial triclosan on the swamp ghost crab (Ucides cordatus; Linnaeus, 1763)

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Nobre, Caio Rodrigues ; Moreno, Beatriz Barbosa ; Alves, Aline Vecchio ; Rosa, Jonas de Lima ; Fontes, Mayana Karoline ; de Campos, Bruno Galvao ; da Silva, Leticia Fernanda ; Duarte, Luis Felipe de Almeida ; Abessa, Denis Moledo de Souza ; Choueri, Rodrigo Brasil ; Gusso-Choueri, Paloma Kachel ; Pereira, Camilo Dias Seabra

• Document type: Journal article
• Source: Chemosphere; v. 304, p. 11-pg., 2022-10-01.

Abstract

Domestic sewage is an important source of pollutants in aquatic ecosystems and includes both microplastics (MPs) and pharmaceuticals and personal care products (PPCPs). This study sought to assess the biological effects of the interaction between plastic particles and the antibacterial agent triclosan (TCS). The study relied on the swamp ghost crab Ucides cordatus as a model. Herein polyethylene particles were contaminated with triclosan solution. Triclosan concentrations in the particles were then chemically analyzed. Swamp ghost crab specimens were exposed to experimental compounds (a control, microplastics, and microplastics with triclosan) for 7 days. Samplings were performed on days 3 (T3) and 7 (T7). Gill, hepatopancreas, muscle and hemolymph tissue samples were collected from the animals to evaluate the biomarkers ethoxyresorufin O-deethylase (EROD), dibenzylfluorescein dealkylase (DBF), glutathione S-transferase (GST), glutathione peroxidase (GPx), reduced glutathione (GSH), lipid peroxidation (LPO), DNA strands break (DNA damage), cholinesterase (ChE) through protein levels and neutral red retention time (NRRT). Water, organism, and microplastic samples were collected at the end of the assay for post-exposure chemical analyses. Triclosan was detected in the water and crab tissue samples, results which indicate that microplastics serve as triclosan carriers. Effects on the gills of organisms (AU)

• FAPESP's process: 17/12193-9 - EVALUATION OF THE ENVIRONMENTAL RISK OF THE INTERACTION OF MICROPLASTIC, DRUG AND ANTIMICROBIAL: AN ECOTOXICOLOGICAL APPROACH
• Grantee: Caio Rodrigues Nobre
• Support Opportunities: Scholarships in Brazil - Doctorate