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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

COMPLEMENTARY AND ALTERNATIVE MEDICINE USE IN BRAZILIAN PATIENTS WITH INFLAMMATORY BOWEL DISEASE

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Author(s):
Débora Pereira HENRIQUES [1] ; Rebeca Rodrigues de OLIVEIRA [2] ; Jeslei VANNI [3] ; Henrique Patriota de LIMA [4] ; Jean Vianney OTITI [5] ; Fabio Ricardo Monteiro NEVES [6] ; Marcia Beiral HAMMERLE [7] ; Lígia Yukie SASSAKI [8] ; Cyrla ZALTMAN [9]
Total Authors: 9
Affiliation:
[1] Universidade Estadual Paulista. Faculdade de Medicina. Departamento de Clínica Médica - Brasil
[2] Universidade Estadual Paulista. Faculdade de Medicina. Departamento de Clínica Médica - Brasil
[3] Universidade Estadual Paulista. Faculdade de Medicina. Departamento de Clínica Médica - Brasil
[4] Universidade Federal do Rio de Janeiro. Faculdade de Medicina. Departamento de Clínica Médica - Brasil
[5] Universidade Federal do Rio de Janeiro. Faculdade de Medicina. Departamento de Clínica Médica - Brasil
[6] Universidade Federal do Rio de Janeiro. Faculdade de Medicina. Departamento de Clínica Médica - Brasil
[7] Universidade Federal do Rio de Janeiro. Faculdade de Medicina. Departamento de Clínica Médica - Brasil
[8] Universidade Estadual Paulista. Faculdade de Medicina. Departamento de Clínica Médica - Brasil
[9] Universidade Federal do Rio de Janeiro. Faculdade de Medicina. Departamento de Clínica Médica - Brasil
Total Affiliations: 9
Document type: Journal article
Source: Arq. Gastroenterol.; v. 59, n. 3, p. 375-382, 2022-09-09.
Abstract

ABSTRACT Background: The conventional treatment of inflammatory bowel disease (IBD) is based on drug therapy, but different studies have shown a progressive increase in the use of complementary and alternative medicine (CAM). The most used CAM comprises of acupuncture, traditional Chinese medicine, Ayurvedic medicine, homeopathy, and herbal medicine, as well as more modern practices, including aromatherapy and reflexology. Data from CAM use in Brazil has previously been scarce and there are no studies among Brazilian patients with IBD. Objective: The aim of the study was to evaluate the frequency of, and factors associated with the use of CAM among IBD patients in Brazil, in addition to estimating the satisfaction with CAM use. Methods: A cross-sectional study was performed in adult IBD outpatients from two Southeastern Brazilian referral centers, with a total a sample of 227 individuals. A semi-structured questionnaire was used containing CAM products - tea, probiotics, omega 3 or glutamine, homeopathy, and herbal therapy, and factors associated with CAM use and patient satisfaction. We used descriptive statistics, association tests (P<0.05) and logistic regression for statistical analyses. Results: In total, 126 patients with Crohn’s disease and 101 with ulcerative colitis were included. The mean age was 41.19±14.49 years and 57.27% were female. The time since diagnosis was 10.58±7.5 years, and most patients were in clinical remission. Twenty-nine patients (12.8%) reported having used CAM for IBD treatment, such as tea (5.29%), probiotics (5.29%), omega-3 or glutamine (1.76%), homeopathy (0.88%), and herbal therapies (0.44%). Despite the low frequency, patients were satisfied (>50%). There was no difference between CAM use in Crohn’s disease as compared to ulcerative colitis patients (P=0.1171). The factors associated with the use of CAM were regular or poor quality of life (odds ratio 2.084; 95% confidence interval 1.147-3.786, P=0.0159) and a shorter time since diagnosis (odds ratio 0.956; 95% confidence interval 0.918-0.995; P=0.0260). Conclusion: The prevalence of CAM use was low, but satisfactory among Brazilian IBD patients. The application of CAM has been associated with poor quality of life and shorter disease duration compared to patients with no use of CAM. (AU)

FAPESP's process: 17/10183-6 - Use of complementary and alternative medicine in patients with inflammatory bowel disease
Grantee:Débora Pereira Henriques
Support Opportunities: Scholarships in Brazil - Scientific Initiation