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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Combined instruments for the screening of dementia in older people with low Education

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Author(s):
Cássio M.C. Bottino [1] ; Sonia E. Zevallos-Bustamante [2] ; Marcos A. Lopes ; Dionisio Azevedo [4] ; Sérgio R. Hototian [5] ; Wilson Jacob-Filho [6] ; Julio Litvoc [7]
Total Authors: 7
Affiliation:
[1] Universidade de São Paulo. Faculdade de Medicina. Instituto e Departamento de Psiquiatria - Brasil
[2] Universidade de São Paulo. Faculdade de Medicina. Instituto e Departamento de Psiquiatria - Brasil
[4] Universidade de São Paulo. Faculdade de Medicina. Instituto e Departamento de Psiquiatria - Brasil
[5] Universidade de São Paulo. Faculdade de Medicina. Instituto e Departamento de Psiquiatria - Brasil
[6] Universidade de São Paulo. Faculdade de Medicina. Departamento de Clínica Médica - Brasil
[7] Universidade de São Paulo. Faculdade de Medicina. Departamento de Medicina Preventiva - Brasil
Total Affiliations: 7
Document type: Journal article
Source: Arquivos de Neuro-Psiquiatria; v. 67, p. 185-190, 2009-06-00.
Abstract

OBJECTIVE: To determine which combination of cognitive tests and informant reports can improve the diagnostic accuracy of dementia screening in low educated older people. METHOD: Patients with mild to moderate dementia (n=34) according to ICD-10 and DSM-III-R criteria and 59 older controls were assessed with the Mini-Mental State Examination (MMSE) and the Fuld Object Memory Evaluation (FOME). Informants were assessed using the Informant Questionnaire on Cognitive Decline in the Elderly and the Bayer-Activities of Daily Living Scale. RESULTS: The 4 instruments combined with the mixed rule correctly classified 100% and the logistic regression (weighted sum) classified 95.7% of subjects. The weighted sum had a significantly larger ROC area compared to MMSE (p=0.008) and FOME (p=0.023). The specificity of the tested combinations was superior to the MMSE alone (p=0.002). CONCLUSIONS: Cognitive tests combined with informant reports can improve the screening of mild to moderate dementia in low educated older people. (AU)