| Full text | |
| Author(s): |
Lopes, Tiago J. S.
;
Rios, Ricardo
;
Nogueira, Tatiane
Total Authors: 3
|
| Document type: | Journal article |
| Source: | BIOINFORMATICS AND BIOLOGY INSIGHTS; v. 16, p. 7-pg., 2022-09-01. |
| Abstract | |
Hemophilia is an inherited blood coagulation disorder caused by mutations on the coagulation factors VIII or IX genes. Although it is a relatively rare disease, the research community is actively working on this topic, producing almost 6000 manuscripts in the last 5 years. Given that the scientific literature is increasing so rapidly. even the most avid reader will find it difficult to follow it closely. In this study, we used sophisticated computational techniques to map the hemophilia literature of the last 60 years. We created a network structure to represent authorship collaborations. where the nodes are the researchers and 2 nodes are connected if they co-authored a manuscript. We accurately identified author clusters, namely, researchers who have collaborated systematically for several years, and used text mining techniques to automatically synthesize their research specialties. Overall. this study serves as a historical appreciation of the effort of thousands of hemophilia researchers and demonstrates that a computational framework is able to automatically identify collaboration networks and their research specialties. Importantly. we made all datasets and source code available for the community, and we anticipate that the methods introduced here will pave the way for the development of systems that generate compelling hypothesis based on patterns that are imperceptible to human researchers. (AU) | |
| FAPESP's process: | 13/07375-0 - CeMEAI - Center for Mathematical Sciences Applied to Industry |
| Grantee: | Francisco Louzada Neto |
| Support Opportunities: | Research Grants - Research, Innovation and Dissemination Centers - RIDC |