Antioxidant Activity of the Ethanol Extract of Salpichlaena Volubilis and Its Correlation with Alopecia Areata

Author(s)

Souza, A. B. ; Medeiros, T. K. S. ; Severino, D. ; Francisco, C. J. ; Uchoa, A. F. ; Bastos-Filho, TF ; Caldeira, EMD ; Frizera-Neto, A

• Document type: Journal article
• Source: XXVII BRAZILIAN CONGRESS ON BIOMEDICAL ENGINEERING, CBEB 2020; v. N/A, p. 7-pg., 2022-01-01.

Abstract

Plants are organisms that produce and store diversity of bioactive substances, between primary and secondary metabolites. Secondaries can have therapeutic properties and are called active ingredients. Salpichlaena volubilis, in Amazonas is known as "Rabo de onca", the parts used as remedies are the leaves and rhizomes. In the scientific literature, no records were found about this species in the treatment of diseases, only reports of use for the treatment of alopecia areata. To evaluate the first technical-scientific essay, two methods were used: the first method used was to capture the organic radical DPPH center dot, the second was to characterize O-1(2).The work aimed to evaluate the antioxidant activity of the ethanol extract of S. volubilis and its correlation with alopecia areata. To compare the determination of antioxidant action, the standard model of capture of organic radicals DPPH center dot/TROLOX and the extracts of S. volubilis were used. The results are presented in the UV/visible absorption spectra and in the kinetics of the extracts, being significant compared with the standard model.The leaf/rhizome extract showed the best suppression of DPPH center dot, 80% in five minutes. In the characterization of the O-1(2) evaluated with emission at 532 nm when excited at different wavelengths, it was possible to observe that the extracts, compared with the blue methylene/acetonitrile model, present singlet oxygen generation. In the emission spectrum of O-1(2) irradiated at 532 nm, the leaf extract/ACN showed a spectral curve characteristic to the generation of 102 with maximum absorption at 1270 nm. While the extracts of the rhizome and leaf/rhizome, had little emission of O-1(2). (AU)

• FAPESP's process: 13/07937-8 - Redoxome - Redox Processes in Biomedicine
• Grantee: Ohara Augusto
• Support Opportunities: Research Grants - Research, Innovation and Dissemination Centers - RIDC