Acquired and Transmitted Multidrug-Resistant Tuberculosis among the Incarcerated Population and Its Determinants in the State of Parana-Brazil

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Dos Santos, Marcio Souza ; Pieri, Flavia Meneguetti ; Berra, Thais Zamboni ; Scholze, Alessandro Rolim ; Vieira Ramos, Antonio Carlos ; Crispim, Juliane de Almeida ; Giacomet, Clovis Luciano ; Alves, Yan Mathias ; Paulino da Costa, Fernanda Bruzadelli ; Dias Moura, Heriederson Savio ; Ayandeyi Teibo, Titilade Kehinde ; Alonso, Jonas Bodini ; de Freitas, Giselle Lima ; Arcencio, Ricardo Alexandre

• Document type: Journal article
• Source: INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH; v. 19, n. 22, p. 12-pg., 2022-11-01.

Abstract

(1) Background: Tuberculosis remains a public health problem in the world. The study analyzed the factors associated with drug-resistant tuberculosis in the prison population of the state of Parana. (2) Methods: Ecological study of drug-resistant tuberculosis cases registered in the Parana Information System, Brazil (2008 to 2018). We performed descriptive statistics of quantitative parameters calculated with absolute frequencies. Additionally, we used binary regression logistics, where the odds ratio with its respective confidence interval was calculated. (3) Results: Of the 653 cases registered as cases of tuberculosis in the incarcerated population, 98 were drug-resistant tuberculosis. We observed that educational level of up to 8 to 11 years of schooling, negative bacterial culture (test outcome) and no tobacco use were factors associated with the non-development of drug-resistant tuberculosis, while clinically confirmed pulmonary TB and positive sputum smear microscopy in the fourth month of follow-up showed an association for the development of drug resistance. (4) Conclusions: The study showed that clinically confirmed pulmonary TB and a positive sputum smear microscopy in the fourth month of follow-up were associated with drug-resistant tuberculosis. (AU)

• FAPESP's process: 20/03361-8 - Determinants associated with multidrug-resistant tuberculosis in the Paraná State prison system
• Grantee: Márcio Souza dos Santos
• Support Opportunities: Scholarships in Brazil - Master