Visible Light-Enhanced C-H Amination of Cyclic Ethers with Iminoiodinanes

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Author(s):	Jurberg, Igor D. ; Nome, Rene A. ; Crespi, Stefano ; Atvars, Teresa D. Z. ; Koenig, Burkhard Total Authors: 5
Document type:	Journal article
Source:	ADVANCED SYNTHESIS & CATALYSIS; v. N/A, p. 9-pg., 2022-11-23.
Abstract
A two-step protocol allowing the C-H amination of cyclic ethers with iminoiodinanes, followed by the reduction of the resulting intermediate has been developed for the preparation of amino alcohols. The initial C-H functionalization is accelerated by visible light, improving the reactivity compared to the thermal process performed in the dark. The effect of different substituents on the photochemical reactivity of iminoiodinanes has been studied both experimentally and computationally. Photophysical measurements and DFT calculations were performed to better understand the observed reactivities and corroborate the proposed mechanistic proposal. (AU)

FAPESP's process:	20/10541-2 - Connecting femtosecond and real-time dynamics through laser spectroscopy and microscopy
Grantee:	René Alfonso Nome Silva
Support Opportunities:	Regular Research Grants


FAPESP's process:	09/14153-8 - Photophysics and electroluminescence of organic polymer and dyes
Grantee:	Teresa Dib Zambon Atvars
Support Opportunities:	Regular Research Grants


FAPESP's process:	19/01235-8 - Photochemistry with visible light using donor-acceptor diazocompounds
Grantee:	Igor Dias Jurberg
Support Opportunities:	Regular Research Grants