Occurrence of clinically relevant antimicrobial resistance genes, including mcr-3 and mcr-7.1, in soil and water from a recreation club

Author(s)

Furlan, Joao Pedro Rueda ; Dos Santos, Lucas David Rodrigues ; Ramos, Micaela Santana ; Gallo, Inara Fernanda Lage ; Moretto, Jessica Aparecida Silva ; Stehling, Eliana Guedes

• Document type: Journal article
• Source: INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH; v. 32, n. 4, p. 10-pg., 2020-08-01.

Abstract

We researched clinically relevant antimicrobial resistance genes (ARGs) and mobile genetic elements (MGEs) in environmental samples from a recreation club in Brazil. A total of 172 amplicons (105 from soil and 67 from water) of 26 ARGs (20 among the soil and water samples; four only in soil samples; two only in water samples) were detected. Nine MGEs were detected, including plasmids and class 1 integron. The absolute abundance of the mcr-3 gene ranged from 1.12 x 10(2) to 1.81 x 10(3) copies/mL(-1) in water samples. The rapid spread of mcr-like genes in several sources has generated a huge concern to public health. Accordingly, understanding of antimicrobial resistance, carry out surveillance studies may contribute to tackle antimicrobial resistance. As the environmental samples were collected from a popular recreation club in Brazil, this study points out to the risk and exposure to clinically relevant ARGs, especially to mcr-3 and mcr-7.1 genes. (AU)

• FAPESP's process: 18/01890-3 - Study of resistance, virulence and epidemiological profile of Escherichia coli isolated from environment
• Grantee: João Pedro Rueda Furlan
• Support Opportunities: Scholarships in Brazil - Doctorate