Biomimetic Biomaterials Based on Polysaccharides: Recent Progress and Future Perspectives

Author(s)

Silva, Rodrigo Duarte ; de Carvalho, Layde Teixeira ; de Moraes, Rodolfo Minto ; Medeiros, Simone de Fatima ; Lacerda, Talita Martins

• Document type: Journal article
• Source: MACROMOLECULAR CHEMISTRY AND PHYSICS; v. N/A, p. 19-pg., 2022-03-04.

Abstract

Nature is a source of diverse materials, including polysaccharides, which have been used to improve the quality of life. Besides being abundant and renewable, polysaccharides possess many advantages, such as biodegradability and biocompatibility, which allow them to be applied in different fields. They can be used in the design and development of renewable materials, thus contributing to a more sustainable society. Because of their advantages and versatility, polysaccharides may be incorporated in many systems, particularly biomimetic ones, to create outstanding sustainable solutions to problems that still need to be solved. Hence, nature not only offers resources but an inspiration to overcome issues. In this sense, this work aims to present an overview of current relevant biomimetic systems based on polysaccharides. Chitosan, cellulose, xanthan gum, alginates, pullulan, hyaluronic acid, schizophyllan, and oligomeric cyclodextrins are covered. The application of these polysaccharides in the design of biosensors, systems for environmental remediation, structural materials, drug delivery systems, tissue engineering among others is described. Finally, the challenges that still need to be faced and opportunities of application of these materials for the development of bioinspired technologies in the next future are highlighted. (AU)

• FAPESP's process: 19/04269-0 - Evaluation of novel polymer nanoparticles as potential carriers for simultaneous release of a photosensitising agent and an active chemotherapeutic agent
• Grantee: Simone de Fátima Medeiros Sampaio
• Support Opportunities: Regular Research Grants
• FAPESP's process: 19/12940-4 - Biodegradable and biocompatible nanoparticles for controlled release of paclitaxel and fluorouracil for the treatment of Hepatocellular Carcinoma (HCC)
• Grantee: Layde Teixeira de Carvalho
• Support Opportunities: Scholarships in Brazil - Doctorate
• FAPESP's process: 20/11104-5 - Whole utilization of fruits processing waste for the production of biopolymer films with UV-blocking properties for biodegradable packaging
• Grantee: Rodrigo Duarte Silva
• Support Opportunities: Scholarships in Brazil - Post-Doctoral