What Are the Effects on Palate of Early Lip Surgery in Children With Cleft Lip and Palate? Cross-Sectional Evaluation From 5-Year-Old

Author(s)

Ambrosio, Eloa Cristina Passucci ; Furiatto, Arthur P. ; Coutinho, Marcelli S. ; Quagliato, Debora R. ; Carrara, Cleide Felicio Carvalho ; Machado, Maria Aparecida Andrade Moreira ; Oliveira, Thais M. ; Jorge, Paula K.

• Document type: Journal article
• Source: JOURNAL OF CRANIOFACIAL SURGERY; v. 34, n. 6, p. 4-pg., 2023-09-01.

Abstract

This study aimed to evaluate the postsurgical effects from 5 years on the palate after surgical repair of the lip at 3 or 9 months of age in children with cleft lip and palate. Eighty-four digitized dental impressions were divided into the following groups: group 1 (G1): lip surgery at 3 months of life; group 2 (G2): lip surgery at 9 months of life; group 3 (G3): without orofacial cleft. Five angular (C'IC, ICM, IC'M', CMM', and C'M'M) and 3 linear parameters (C-C', c-c', and M-M') were evaluated. Statistical analysis was applied with a=5%. Intra-class Correlation Coefficient was significantly smaller in G1 than in G3 (P=0.005), while IC'M' was significantly smaller in G3 than in G1 (P<0.001). C'M'M was significantly smaller in G1 than in G2 and G3 (P<0.001). The distances C-C' and c-c' were significantly smaller in G1 than in G2 and G3 (P<0.001). There was a statistically significant difference in both G1 and G2 (P<0.001, in all) in the analysis of palatal symmetry. Linear regression analysis showed that the, 11.2% of outcomes determined by c-c' distance can be explained by the age of lip repair (P=0.013). In conclusion, lip surgery at 3 months of life showed a tendency toward more restriction in 5-year post-surgery palate development. The age of cheiloplasty is one of the factors that can influence palatal development; however, other factors may be associated and should be studied. (AU)

• FAPESP's process: 21/12424-6 - Rehabilitation protocol with digital workflow in children with cleft lip and palate
• Grantee: Thais Marchini de Oliveira Valarelli
• Support Opportunities: Regular Research Grants
• FAPESP's process: 20/16727-0 - Lip repair consequences in children with cleft lip and palate: 3D evaluation of dental arch linear measurements
• Grantee: Débora Rangel Quagliato
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• FAPESP's process: 20/16690-0 - Innovation in the rehabilitation protocol with digital workflow in children with cleft lip and palate
• Grantee: Eloá Cristina Passucci Ambrosio
• Support Opportunities: Scholarships in Brazil - Post-Doctoral