Multiple biomarkers response of Astyanax lacustris (Teleostei: Characidae) exposed to manganese and temperature increase

Full text
Author(s):	Gnocchi, Karla Giavarini ; Boldrini-Franca, Johara ; Passos, Larissa Souza ; Gomes, Aline Silva ; Coppo, Gabriel Carvalho ; Pereira, Tatiana Miura ; Chippari-Gomes, Adriana Regina Total Authors: 7
Document type:	Journal article
Source:	ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY; v. 100, p. 7-pg., 2023-04-19.
Abstract
The present study aimed to evaluate the toxicity of Mn (6.65 mg/L) at different exposure times (96 h, 7, 14, and 21 days) and evaluate its possible toxic effects on the fish Astyanax lacustris through multi-biomarkers and the maximum critical temperature (CT Max). The results show an increase in the Mn accumulation (liver and gills) with increasing exposure time. The glutathione S-transferase (GST) activity showed differences in the group exposed to Mn for 96 h compared to the group exposed for 21 days. The acetylcholinesterase (AChE) activity increased in the fish exposed for 7 days compared to the control group. On the other hand, no genotoxic changes were observed. The CT Max showed that the loss of equilibrium of 50% of the fish occurs at a temperature of 39oC, with and without the Mn presence. Furthermore, the catalase gene expression (oxidative stress) did not show alterations. (AU)

FAPESP's process:	21/14239-1 - Effects of interaction between synthetic and natural organophosphates on Oreochromis niloticus (Teleostei: Cichlidae)
Grantee:	Larissa Souza Passos
Support Opportunities:	Scholarships in Brazil - Doctorate