Currently, metals have been responsible for contamination of aquatic ecosystems. In this context it is included aluminum (Al) and manganese (Mn), as result of human actions that cause changes in aquatic environments, such as the decline of natural fish populations and deleterious effects on aquatic organisms. Among these effects, we can highlight the changes in respiratory, metabolic and endocrine systems, the latter being the focus of this project, since metals can act as endocrine disrupters. Some studies show that both metals are able to alter the concentrations of gonadotropins and gonadal steroid hormones, apart from altering the hypothalamic functions, leading to damage to reproduction in females. Considering these endocrine changes in female fish, we will examine the effects caused by metals (Al and Mn) on the concentration of steroid hormones: testosterone, 11-cetotestosterona, 17±-hydroxyprogesterone, estradiol and cortisol in adult male of "lambari do rabo amarelo" (Astyanax bimaculatus Linnaeus, 1758), as well as analysis of the presence of vitellogenin in the mucus, an important biomarker of endocrine disruptors with estrogenic activity. Since data on the influence of these metals on the reproductive physiology of fish are scarce, especially in males, this study will provide important data on the influence of metals on the endocrine system of fish, and may contribute to future studies aimed at greater ecological amplitude, aiming the reproductive success of these animals and thus the perpetuation of the species.
News published in Agência FAPESP Newsletter about the scholarship: