Determination of Acrylamide in Commercial Baby Foods by LC-QqQ-MS/MS: a Simple Method for Routine Analyses

Author(s)

Prata, Rafaela ; Vargas Perez, Marta ; Petrarca, Mateus Henrique ; Godoy, Helena Teixeira ; Frenich, Antonia Garrido ; Romero-Gonzalez, Roberto

• Document type: Journal article
• Source: FOOD ANALYTICAL METHODS; v. N/A, p. 9-pg., 2023-06-28.

Abstract

A method based on liquid chromatography-triple quadrupole tandem mass spectrometry was developed and validated for the analysis of acrylamide in baby foods. The sample preparation involves a simple extraction process using a mixture of acetonitrile:water:formic acid (69:30:1, v/v/v) in combination with dispersive solid-phase extraction (d-SPE) using alumina as sorbent. The method shown good linearity within the range 20-250 & mu;g kg(-1) through matrix-matched and solvent calibrations. The recovery rates for acrylamide ranged from 100 to 108% with coefficients of variation below 10%, under repeatability and reproducibility conditions (within-laboratory). The obtained limit of quantification (20 & mu;g kg(-1)) complies with the values indicated by the European Union for acrylamide analysis in baby foods. The developed and validated method was applied to 50 ready-to-eat baby foods available in the Brazilian market. Acrylamide was detected in 13% of samples primarily composed of fruits, whereas it was found in approximately 37% of baby food containing meat and/or vegetables. Additionally, in 2 samples, the detected levels exceeded the benchmark value established by the EU (40 & mu;g kg(-1)). The study showcases the applicability of this method for routine analysis of acrylamide detection. (AU)

• FAPESP's process: 19/04727-9 - Development and validation of analytical methods for the determination of processing contaminants and agrochemical residues in baby foods
• Grantee: Rafaela Prata
• Support Opportunities: Scholarships in Brazil - Doctorate (Direct)
• FAPESP's process: 20/01974-2 - Determination of residues and contaminants in baby foods marketed in Brazil by UHPLC-QqQ-MS/MS: development and validation of methods
• Grantee: Rafaela Prata
• Support Opportunities: Scholarships abroad - Research Internship - Doctorate (Direct)