| Full text | |
| Author(s): Show less - |
Silva, Fernando de Sa
;
Almeida, Paula Nascimento
;
Paes Rettore, Joao Vitor
;
Maranduba, Claudineia Pereira
;
de Souza, Camila Maurmann
;
de Souza, Gustavo Torres
;
Salomao Zanette, Rafaella de Souza
;
Harumi Miyagi, Sueli Patricia
;
Santos, Marcelo de Oliveira
;
Marques, Marcia Martins
;
da Costa Maranduba, Carlos Magno
Total Authors: 11
|
| Document type: | Journal article |
| Source: | JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY; v. N/A, p. 12-pg., 2012-01-01. |
| Abstract | |
Stem cells, both embryonic and adult, due to the potential for application in tissue regeneration have been the target of interest to the world scientific community. In fact, stem cells can be considered revolutionary in the field of medicine, especially in the treatment of a wide range of human diseases. However, caution is needed in the clinical application of such cells and this is an issue that demands more studies. This paper will discuss some controversial issues of importance for achieving cell therapy safety and success. Particularly, the following aspects of stem cell biology will be presented: methods for stem cells culture, teratogenic or tumorigenic potential, cellular dose, proliferation, senescence, karyotyping, and immunosuppressive activity. (AU) | |
| FAPESP's process: | 10/09491-9 - Investigation of immunomodulatory aspects of human immature dental pulp stem cells |
| Grantee: | Fernando de Sá Silva |
| Support Opportunities: | Scholarships in Brazil - Doctorate |
| FAPESP's process: | 09/00510-3 - Analysis of hematopoetic reconstitution in irradiated mice after infusion of human immature dental pulp stem cells |
| Grantee: | Carlos Magno da Costa Maranduba |
| Support Opportunities: | Scholarships in Brazil - Young Researchers |