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Insights on bovine genetic engineering and cloning

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Author(s):
Bressan, Fabiana F. ; Sangalli, Juliano R. ; Pessa, Lais V. F. ; Pires, Pedro R. L. ; Meirelles, Flavio V.
Total Authors: 5
Document type: Journal article
Source: Pesquisa Veterinária Brasileira; v. 33, p. 6-pg., 2013-12-01.
Abstract

Transgenic technology has become an essential tool for the development of animal biotechnologies, and animal cloning through somatic cell nuclear transfer (SCNT) enabled the generation of genetically modified animals utilizing previously modified and selected cell lineages as nuclei donors, assuring therefore the generation of homogeneous herds expressing the desired modification. The present study aimed to discuss the use of SCNT as an important methodology for the production of transgenic herds, and also some recent insights on genetic modification of nuclei donors and possible effects of gene induction of pluripotency on SCNT. (AU)

FAPESP's process: 08/57877-3 - National Institute of Science and Technology in Cell Therapy
Grantee:Roberto Passetto Falcão
Support Opportunities: Research Projects - Thematic Grants
FAPESP's process: 11/08376-4 - Effects of genetic induction and reprogramming through nuclear transfer in in vitro bovine embryo production
Grantee:Flávio Vieira Meirelles
Support Opportunities: Regular Research Grants
FAPESP's process: 09/11631-6 - EFFECTS OF GENE INDUCTION AND NUCLEAR TRANFER REPROGRAMMING IN BOVINE IN VITRO EMBRYO PRODUCTION
Grantee:Fabiana Fernandes Bressan
Support Opportunities: Scholarships in Brazil - Doctorate
FAPESP's process: 08/00102-0 - Production of bovine transgenic embryos for the coagulation factor IX
Grantee:Paulo Sérgio Monzani
Support Opportunities: Scholarships in Brazil - Post-Doctoral