Contact with Fluoride-Releasing Restorative Materials Can Arrest Simulated Approximal Caries Lesion

Author(s)

Brandao Guglielmi, Camila de Almeida ; Bissoto Calvo, Ana Flavia ; Tedesco, Tamara Kerber ; Mendes, Fausto Medeiros ; Raggio, Daniela Procida

• Document type: Journal article
• Source: Journal of Nanomaterials; v. 2015, p. 7-pg., 2015-01-01.

Abstract

Previous studies have suggested that the presence of white-spot lesion is very probable when adjacent surface is affected by cavitated lesions. This study evaluated the potential of different fluoride-releasing restorative materials in arresting enamel white-spot lesions in approximal surface in contact with them, in vitro (I) and in situ (II). White-spot lesions were formed in 240 primary enamel specimens via pH-cycling. They were put in contact with cylindrical blocks of 6 materials (n = 20): composite resin, 2 high-viscous glass ionomer cements (HVGIC), resin-modified GIC, resin-modified nanoionomer, and polyacid-modified resin. In both studies I and II, these settings were designed to simulate the contact point between the restoration and simulated approximal lesion. For study I, they were subjected to a new pH-cycling cariogenic challenge for 7 or 14 days (n = 10). For study II, a randomized double-blind in situ design was conducted in two phases (7/14 days) to promote cariogenic challenge. At the end of both studies, specimens were collected for mineral analysis by cross-sectional microhardness. Higher mineral loss was observed for lesions in contact with resin (p < 0.001). HVGICs were the most efficient in preventing mineral loss, whereas other materials presented an intermediate behavior. It is concluded that fluoride-releasing materials can moderately reduce white-spot lesions progression, and HVGIC can arrest enamel lesion in approximal surface in contact with them. (AU)

• FAPESP's process: 10/16120-7 - In vitro and in situ remineralization of approximal lesions in contact with different dental materials in primary teeth
• Grantee: Daniela Prócida Raggio
• Support Opportunities: Regular Research Grants