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Per3 expression in different tissues of Cebus apella

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Author(s):
Sabinoa, Flavia Cal ; de Oliveira, Jose Americo ; Pedrazzoli, Mario
Total Authors: 3
Document type: Journal article
Source: SLEEP SCIENCE; v. 9, n. 4, p. 4-pg., 2016-10-01.
Abstract

We present a study of Per3 expression in six different tissues of the non-human primate Cebus apella (capuchin monkey). The aim of this study was to verify whether the expression of the Per3 gene in different tissues of capuchin monkey occurs in a circadian pattern, its phase and the phase relationships between these different tissues during the 24 h of a day. We observed that gene expression oscillated in all of the tissues studied during this time period, although only the liver and muscle presented a robust circadian pattern. This preliminary study highlights the possibility of using Cebus apella as a model to study circadian rhythms at the gene expression level and opens an opportunity for future researches. (AU)

FAPESP's process: 11/05804-5 - Phenotypic characterization of circadian rhythms in different genotype individuals for clock gene polymorphisms in different regions in Brazil: an emphasis on the effect of the gene PER3 and latitude
Grantee:Mario Pedrazzoli Neto
Support Opportunities: Regular Research Grants