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Cacipacore virus as an emergent mosquito-borne Flavivirus

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Garcia de Figueiredo, Mario Luis ; Amarilla, Alberto Anastacio ; de Figueiredo, Glauciane Garcia ; Alfonso, Helda Liz ; Lippi, Veronica ; Motta Maia, Felipe Goncalves ; Morais, Felipe Alves ; da Costa, Cristovao Alves ; Henriques, Dyana Alves ; Durigon, Edison Luis ; Moraes Figueiredo, Luiz Tadeu ; Aquino, Victor Hugo
Total Authors: 12
Document type: Journal article
Source: Revista da Sociedade Brasileira de Medicina Tropical; v. 50, n. 4, p. 4-pg., 2017-07-01.
Abstract

Introduction: Cacipacore virus (CPCV), a possible bird-associated flavivirus, has yet to be detected in mosquitoes. Our purpose is examining CPCV in mosquitoes from the Amazon region of Brazil. Methods: Approximately 3,253 Culicidae (grouped into 264 pools) were collected from the Amazon region during 2002-2006 and analyzed using a Flavivirus genus-specific reverse transcription-polymerase chain reaction followed by nested polymerase chain reaction assay and by nucleotide sequencing of amplicons. Results: Nucleotide sequences from five mosquito samples showed high similarity to the those of CPCV originally isolated in the Amazon region. Conclusions: This is the first report of CPCV-infected mosquitoes which has implications on the arbovirus maintenance in nature and transmission to man. (AU)

FAPESP's process: 15/04882-3 - Identification and characterization of viruses causing fever diseases and transmitted by arthropods and rodents in the region of Porto Velho, Rondônia
Grantee:Mario Luis Garcia de Figueiredo
Support Opportunities: Scholarships in Brazil - Post-Doctoral