Active ingredients, mechanisms of action and efficacy tests of antipollution cosmetic and personal care products

Author(s)

Robles Velasco, Maria Valeria ; Sauce, Rafael ; de Oliveira, Camila Areias ; de Oliveira Pinto, Claudineia A. S. ; Martinez, Renata Miliani ; Baah, Stephanie ; Almeida, Tania Santos ; Rosado, Catarina ; Baby, Andre Rolim

• Document type: Journal article
• Source: Brazilian Journal of Pharmaceutical Sciences; v. 54, p. 8-pg., 2018-01-01.

Abstract

Urban population around the globe is direct exposed to the pollution caused by several sources (vehicles, industries, smokes etc.) and primary pollutants are divided in particulate matter and toxic gases. Current researches in populous countries indicated that exposure to pollution could affect sebum composition, stratum corneum quality and signs of skin aging. Hair and scalp are also affected by the excessive exposure to pollutants, resulting in a dull, dry and lifeless appearance. Cosmetics have been evolved conceptual and scientifically to achieve substantial effectiveness against pollution damaging on the cutaneous tissue, involving the development of innovative multipurpose active ingredients and efficacy tests, skilled to prove the protection and benefits of such personal care products. In this review, we highlighted the skin and hair/scalp damages provoked by the main environmental pollutants and the active substances used in antipollution cosmetics/personal care products with the respective mechanisms of action. Likewise, in vitro and in vivo efficacy tests were discussed concerning the antipollution claim substantiating. (AU)

• FAPESP's process: 16/24360-4 - Antilipoperoxidative and anti-inflammatory effects of multifunctional sunscreens containing ferulic acid
• Grantee: André Rolim Baby
• Support Opportunities: Regular Research Grants