| Full text | |
| Author(s): |
Linzke, Marleen
;
Yan, Sun Liu Rei
;
Tarnok, Attila
;
Ulrich, Henning
;
Groves, Matthew R.
;
Wrenger, Carsten
Total Authors: 6
|
| Document type: | Journal article |
| Source: | Cytometry Part A; v. 97, n. 7, p. 12-pg., 2019-11-18. |
| Abstract | |
Malaria remains one of the deadliest diseases worldwide and it is caused by the protozoan parasite Plasmodium spp. Parasite visualization is an important tool for the correct detection of malarial cases but also to understand its biology. Advances in visualization techniques promote new insights into the complex life cycle and biology of Plasmodium parasites. Live cell imaging by fluorescence microscopy or flow cytometry are the foundation of the visualization technique for malaria research. In this review, we present an overview of possibilities in live cell imaging of the malaria parasite. We discuss some of the state-of-the-art techniques to visualize organelles and processes of the parasite and discuss limitation and advantages of each technique. (c) 2019 International Society for Advancement of Cytometry (AU) | |
| FAPESP's process: | 17/03966-4 - Targeting lipoic acid salvage and biosynthesis pathways in MRSA |
| Grantee: | Carsten Wrenger |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 12/50880-4 - Stem cells: from basic studies of kinin and purinergic receptor roles towards therapeutical applications |
| Grantee: | Alexander Henning Ulrich |
| Support Opportunities: | Research Projects - Thematic Grants |
| FAPESP's process: | 14/23330-9 - Morphologic Analysis of the Apicoplast Formation in Plasmodium falciparum |
| Grantee: | Marleen Linzke |
| Support Opportunities: | Scholarships in Brazil - Doctorate |
| FAPESP's process: | 12/50393-6 - Aptamers for diagnostic marker and therapeutic inhibitor discovery in infectious diseases |
| Grantee: | Alexander Henning Ulrich |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 17/26358-0 - Dissection of the lipoic acid metabolism as druggable target in Malaria |
| Grantee: | Sun Liu Rei Yan |
| Support Opportunities: | Scholarships in Brazil - Doctorate |
| FAPESP's process: | 15/26722-8 - Drug discovery against human infectious diseases |
| Grantee: | Carsten Wrenger |
| Support Opportunities: | Research Projects - Thematic Grants |