| Full text | |
| Author(s): |
Heubel, Alessandro Domingues
;
Roscani, Meliza Goi
;
Kabbach, Erika Zavaglia
;
Agnoleto, Aline Galvao
;
Camargo, Patricia Faria
;
dos Santos, Polliana Batista
;
Borghi-Silva, Audrey
;
Mendes, Renata Goncalves
Total Authors: 8
|
| Document type: | Journal article |
| Source: | Journal of Cardiopulmonary Rehabilitation and Prevention; v. 40, n. 5, p. 4-pg., 2020-09-01. |
| Abstract | |
Purpose: Chronic obstructive pulmonary disease (COPD) and abnormalities of left ventricular (LV) geometry often coexist. This study aimed to verify whether LV geometry is associated with airflow obstruction, functional capacity, and grip strength in COPD patients. Methods: Thirty-seven COPD patients (GOLD II, III, and IV) were allocated to three groups according to LV geometry as assessed by transthoracic echocardiography: normal (n = 13), concentric LV remodeling (n = 8), and concentric LV hypertrophy (LVH) (n = 16). Lung function was assessed using spirometry. The Duke Activity Status Index (DASI) was used to estimate functional capacity, and grip strength measurement was performed using a hydraulic hand dynamometer. Results: The concentric LVH group presented lower DASI scores (P= .045) and grip strength (P= .006) when compared with the normal group. Correlations analysis showed the following: relative wall thickness negatively correlated with forced expiratory volume in the first second (r= -0.380;P= .025) and DASI score (r= -0.387,P= .018); LV mass index negatively correlated with grip strength (r= -0.363,P= .038). Conclusions: In COPD patients, LV geometry is associated with airflow limitation, functional capacity, and grip strength. Specifically, concentric LV remodeling is associated with increased airflow limitation and decreased functional capacity whereas increased LV mass is associated with decreased grip strength. (AU) | |
| FAPESP's process: | 15/12763-4 - Exacerbation of COPD and COPD overlap heart failure and noninvasive ventilatory support: impact on endothelial function and cardiac autonomic modulation and relationship among cardiovascular outcomes and clinical and functional aspects |
| Grantee: | Renata Gonçalves Mendes |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 18/00860-3 - Evaluation of cardiac autonomic modulation and functional capacity in the overlap of Chronic Obstructive Pulmonary Disease and Obstructive Sleep Apnea Syndrome: a follow-up study |
| Grantee: | Patrícia Faria Camargo |
| Support Opportunities: | Scholarships in Brazil - Doctorate (Direct) |
| FAPESP's process: | 18/03314-0 - Follow-up of cardiorrespiratory changes and its impact on capacity of physical exercise in patients with heart failure and COPD overlap |
| Grantee: | Polliana Batista dos Santos |
| Support Opportunities: | Scholarships in Brazil - Doctorate (Direct) |
| FAPESP's process: | 15/26501-1 - Study of limiting factors to physical exercise and adjunct effects to rehabilitation on cardiorespiratory disease: a multicentre approach |
| Grantee: | Audrey Borghi Silva |
| Support Opportunities: | Research Projects - Thematic Grants |