Deciphering the total RNA content of extracellular vesicles

Advanced search

Search - Use quotation marks to get a more specific result

Index

Field of knowledge

Start date

Betweenand

Full text
Author(s):	Amorim, Maria G. ; Dias-Neto, Emmanuel ; Nunes, Diana N. ; Spada, S ; Galluzzi, L Total Authors: 5
Document type:	Journal article
Source:	EXTRACELLULAR VESICLES; v. 645, p. 14-pg., 2020-01-01.
Abstract
Extracellular vesicles (EVs) have been recognized as relevant players in cell-cell communication. To fully explore their potential as carriers of biological information in clinical settings, protocols capable of dealing with minute amounts of proteins, lipids, and nucleic acids present in their cargo are a requirement. Here we delve into a protocol to decipher the total transcriptome of EVs, from undetectable amounts of EVs-derived RNA from clinical samples. (AU)

FAPESP's process:	11/09172-3 - Evaluation of circulating microparticles derived from invasive ductal breast adenocarcinomas Her2+ patients and it's possible correlation with tumor aggressiveness
Grantee:	Emmanuel Dias-Neto
Support Opportunities:	Regular Research Grants


FAPESP's process:	14/26897-0 - Epidemiology and genomics of gastric adenocarcinomas in Brazil
Grantee:	Emmanuel Dias-Neto
Support Opportunities:	Research Projects - Thematic Grants