| Full text | |
| Author(s): |
Marly A Cardoso
[1]
;
Bárbara H. Lourenço
[2]
;
Alicia Matijasevich
[3]
;
Marcia C Castro
[4]
;
Marcelo U Ferreira
[5]
Total Authors: 5
|
| Affiliation: | [1] Universidade de São Paulo. Faculdade de Saúde Pública. Departamento de Nutrição - Brasil
[2] Universidade de São Paulo. Faculdade de Saúde Pública. Departamento de Nutrição - Brasil
[3] Universidade de São Paulo. Faculdade de Medicina. Departamento de Medicina Preventiva - Brasil
[4] Harvard T.H. Chan School of Public Health. Department of Global Health and Population
[5] Universidade de São Paulo. Instituto de Ciências Biomédicas. Departamento de Parasitologia - Brasil
Total Affiliations: 5
|
| Document type: | Journal article |
| Source: | Revista de Saúde Pública; v. 57, 2024-02-26. |
| Abstract | |
ABSTRACT OBJECTIVE: This study aimed to describe the prevalence and predictors of childhood anemia in an Amazonian population-based birth cohort study. METHODS: Prevalence of maternal anemia was estimated at delivery (hemoglobin [Hb] concentration < 110 g/L) in women participating in the MINA-Brazil birth cohort study and in their children, examined at ages one, two (Hb < 110 g/L), and five (Hb < 115 g/L). Moreover, ferritin, soluble transferrin receptor, and C-reactive protein concentrations were measured in mothers at delivery and in their 1- and 2-year-old children to estimate the prevalence of iron deficiency and its contribution to anemia, while adjusting for potential confounders by multiple Poisson regression analysis (adjusted relative risk [RRa]). RESULTS: The prevalence 95% confidence interval (CI) of maternal anemia, iron deficiency, and iron-deficiency anemia at delivery were 17.3% (14.0–21.0%), 42.6% (38.0–47.2%), and 8.7% (6.3–11.6)%, respectively (n = 462). At one year of age (n = 646), 42.2% (38.7–45.8%) of the study children were anemic, 38.4% (34.6–42.3%) were iron-deficient, and 26.3 (23.0–29.9) had iron-deficiency anemia. At two years of age (n = 761), these values decreased to 12.8% (10.6–15.2%), 18.1% (15.5–21.1%), and 4.1% (2.8–5.7%), respectively; at five years of age (n = 655), 5.2% (3.6–7.2%) were anemic. Iron deficiency (RRa = 2.19; 95%CI: 1.84–2.60) and consumption of ultra-processed foods (UPF) (RRa = 1.56; 95%CI: 1.14–2.13) were significant contributors to anemia at 1 year, after adjusting for maternal schooling. At 2 years, anemia was significantly associated with maternal anemia at delivery (RRa: 1.67; 95%CI: 1.17–2.39), malaria since birth (2.25; 1.30–3.87), and iron deficiency (2.15; 1.47–3.15), after adjusting for children's age and household wealth index. CONCLUSIONS: Anemia continues to be highly prevalent during pregnancy and early childhood in the Amazon. Public health policies should address iron deficiency, UPF intake, maternal anemia, and malaria to prevent and treat anemia in Amazonian children. (AU) | |
| FAPESP's process: | 16/00270-6 - MINA study - Maternal and child health in Acre: birth cohort in the Western Brazilian Amazon |
| Grantee: | Marly Augusto Cardoso |
| Support Opportunities: | Research Projects - Thematic Grants |