Lower Urinary Tract Symptoms in a prospective cohort of COVID-19 survivors

Author(s):Show less -

Cristiano M. Gomes ^[1] ; Marcelo Hisano ^[2] ; Julia D. Souza ^[3] ; João Victor T. Henriques ^[4] ; Jose de Bessa Jr. ^[5] ; Julyana Moromizato ^[6] ; Thulio Bosi ^[7] ; Rachel Mazoni ^[8] ; João Gismondi ^[9] ; Bruno Camargo ^[10] ; Zein M. Sammour ^[11] ; Homero Bruschini ^[12] ; Linamara R. Battistella ^[13] ; William C. Nahas ^[14]

Affiliation:Show less -

^[1] Faculdade de Medicina da Universidade de São Paulo. Divisão de Urologia - Brasil

^[2] Faculdade de Medicina da Universidade de São Paulo. Divisão de Urologia - Brasil

^[3] Faculdade de Medicina da Universidade de São Paulo. Divisão de Urologia - Brasil

^[4] Faculdade de Medicina da Universidade de São Paulo. Divisão de Urologia - Brasil

^[5] Universidade Estadual de Feira de Santana. Departamento de Cirurgia - Brasil

^[6] Faculdade de Medicina da Universidade de São Paulo. Divisão de Urologia - Brasil

^[7] Faculdade de Medicina da Universidade de São Paulo. Divisão de Urologia - Brasil

^[8] Faculdade de Medicina da Universidade de São Paulo. Divisão de Urologia - Brasil

^[9] Faculdade de Medicina da Universidade de São Paulo. Divisão de Urologia - Brasil

^[10] Faculdade de Medicina da Universidade de São Paulo. Divisão de Urologia - Brasil

^[11] Faculdade de Medicina da Universidade de São Paulo. Divisão de Urologia - Brasil

^[12] Faculdade de Medicina da Universidade de São Paulo. Divisão de Urologia - Brasil

^[13] Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo. Instituto de Medicina Física e de Reabilitação - Brasil

^[14] Faculdade de Medicina da Universidade de São Paulo. Divisão de Urologia - Brasil

• Document type: Journal article
• Source: INTERNATIONAL BRAZ J UROL; v. 50, n. 3, p. 287-295, 2024-05-27.

Abstract

ABSTRACT Purpose: To analyze the prevalence of lower urinary tract symptoms (LUTS) in patients who survived moderate and severe forms of COVID-19 and the risk factors for LUTS six months after hospitalization. Materials and Methods: In this prospective cohort study, patients were evaluated six months after hospitalization due to COVID-19. LUTS were assessed using the International Prostate Symptom Score. General health was assessed through the Hospital Anxiety and Depression Scale and the EQ5D-L5 scale, which evaluates mobility, ability to perform daily activities, pain and discomfort and completed a self-perception health evaluation. Results: Of 255 participants, 54.1% were men and the median age was 57.3 [44.3 – 66.6] years. Pre-existing comorbidities included diabetes (35.7%), hypertension (54.5%), obesity (30.2%) and physical inactivity (65.5%). One hundred and twenty-four patients (48.6%) had a hospital stay >15 days, 181 (71.0%) were admitted to an ICU and 124 (48.6%) needed mechanical ventilation. Median IPSS was 6 [3-11] and did not differ between genders. Moderate to severe LUTS affected 108 (42.4%) patients (40.6% men and 44.4% women; p=0.610). Nocturia (58.4%) and frequency (45.9%) were the most prevalent symptoms and urgency was the only symptom that affected men (29.0%) and women (44.4%) differently (p=0.013). LUTS impacted the quality of life of 60 (23.5%) patients with women more severely affected (p=0.004). Diabetes, hypertension, and self-perception of worse general health were associated with LUTS. Conclusions: LUTS are highly prevalent and bothersome six months after hospitalization due to COVID-19. Assessment of LUTS may help ensure appropriate diagnosis and treatment in these patients. (AU)

• FAPESP's process: 22/01769-5 - Late assessment of physical, psychological and cognitive effects in a cohort of patients surviving COVID-19 hospitalization at a tertiary university hospital: a multidisciplinary approach
• Grantee: Carlos Roberto Ribeiro de Carvalho
• Support Opportunities: Research Projects - Thematic Grants