Sjogren's disease, occupational performance and quality of life

Author(s)

Cintra, Beatriz Carneiro ; Marzola, Mateus Maia ; Carretta, Regina Yoneko Dakuzaku ; Oliveira, Fabiola Reis ; Rocha, Eduardo Melani

• Document type: Journal article
• Source: BRITISH JOURNAL OF OCCUPATIONAL THERAPY; v. N/A, p. 8-pg., 2024-09-30.

Abstract

Introduction: Sjogren's disease is an autoimmune disease with dry eyes and mouth and chronic pain, more frequent in middle-aged women. The aim of this study is to understand the impact of Sjogren's disease on quality of life and occupational health. Method: Quantitative and qualitative comparative study, with 20 Sjogren's disease and 25 healthy controls. Questionnaires and interviews were applied to assess occupational performance, quality of life, mood disorders, and sleep. Results: The combined major diagnostic parameters for Sjogren's disease (focus score and anti-SSA/Ro positivity) were present in 85% of the Sjogren's disease group. There was a correlation between the sicca symptom measured by the European League Against Rheumatism Sjogren's Syndrome Patient Reported Index (ESSPRI), anxiety, and depression measured by the Hospital Anxiety and Depression Scale (HADS; r = 0.56; p = 0.009), as well as fatigue measured by the Profile of fatigue and discomfort questionnaire (PROFAD) (r = 0.78; p < 0.0001). Sjogren's disease patients reported a loss of physical abilities, sleep disturbance, change in mood, social and occupational participation, and lower quality of life. Conclusions: Sjogren's disease patients have poorer quality of life, loss of competencies, and sleep disturbances compared to controls. Novel strategies are necessary to improve occupational health in SjD. (AU)

• FAPESP's process: 14/23211-0 - The natural history of lacrimal and salivary gland dysfunction in Sjögren's syndrome
• Grantee: Eduardo Melani Rocha
• Support Opportunities: Regular Research Grants
• FAPESP's process: 22/03521-0 - Investigation of physical methods associated with drug delivery systems in the local immune and antimicrobial response
• Grantee: Renata Fonseca Vianna Lopez
• Support Opportunities: Research Projects - Thematic Grants