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Glass ionomer cement with calcium-releasing particles: Effect on dentin mineral content and mechanical properties

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Author(s):
Vilela, Handially S. ; Resende, Mariana C. A. ; Trinca, Rafael B. ; Scaramucci, Tais ; Sakae, Leticia O. ; Braga, Roberto R.
Total Authors: 6
Document type: Journal article
Source: Dental Materials; v. 40, n. 2, p. 8-pg., 2024-02-08.
Abstract

Objective: to evaluate the effect a glass ionomer cement (GIC) containing hydroxyapatite (HAp) or calcium silicate (CaSi) particles on mineral content and mechanical properties of demineralized dentin. Ion release and compressive strength (CS) of the cements were also evaluated. Methods: GIC (Fuji 9 Gold Label, GC), GIC+ 5%HAp and GIC+ 5%CaSi (by mass) were evaluated. Ion release was determined by induced coupled plasma optical emission spectroscopy (Ca2+/Sr2+) or ion -specific electrode (F-) (n = 3). A composite (Filtek Z250, 3 M ESPE) was used as control in remineralization tests. Demineralized dentin discs were kept in contact with materials in simulated body fluid (SBF) at 37 C-degrees for eight weeks. Mineral:matrix ratio (MMR) was determined by ATR-FTIR spectroscopy (n = 5). Dentin hardness (H) and elastic modulus (E) were determined by nanoindentation (n = 10). CS was tested after 24 h and 7d in deionized water (n = 12). Data were analyzed by ANOVA/Tukey test (alpha = 0.05). Results: Ca2+ and Sr2+ release was higher for the modified materials (p < 0.05). Only GIC+ 5%HAp showed higher F- release than the control (p < 0.05). All groups showed statistically significant increases in MMR, with no differences among them after 8 weeks (p > 0.05). No differences in dentin H or E were observed among groups (p > 0.05). HAp-modified GIC showed increased initial CS, while adding CaSi had the opposite effect (p < 0.05). After 7 days, GIC+ 5%CaSi presented lower CS in relation to control and GIC+ 5%HAp (p < 0.05). Significance: GIC modification with HAp or CaSi affected CS and increased ion release; however, none of the groups showed evidence of dentin remineralization in comparison to the negative control. (AU)

FAPESP's process: 20/06313-4 - Investigation of an alternative to enhance the protection of the acquired salivary pellicle against dental erosion by the association of film-forming polymers and sodium fluoride
Grantee:Taís Scaramucci Forlin
Support Opportunities: Regular Research Grants
FAPESP's process: 20/12761-0 - In vitro analysis of dentin remineralization using glass ionomer cement with or without calcium orthophosphate particles or with mineral trioxide aggregate
Grantee:Handially dos Santos Vilela
Support Opportunities: Scholarships in Brazil - Doctorate (Direct)
FAPESP's process: 20/13983-6 - Effect of temperature, pH and precursors concentrations on the synthesis of DCPD particles and its application on a remineralizing resin composite
Grantee:Rafael Bergamo Trinca
Support Opportunities: Scholarships in Brazil - Post-Doctoral