| Full text | |
| Author(s): |
Mercante, Luiza A.
;
Teodoro, Kelcilene B. R.
;
dos Santos, Danilo M.
;
dos Santos, Francisco V.
;
Ballesteros, Camilo A. S.
;
Ju, Tian
;
Williams, Gareth R.
;
Correa, Daniel S.
Total Authors: 8
|
| Document type: | Journal article |
| Source: | POLYMERS; v. 15, n. 21, p. 26-pg., 2023-11-01. |
| Abstract | |
Electrospun nanofibrous membranes have garnered significant attention in antimicrobial applications, owing to their intricate three-dimensional network that confers an interconnected porous structure, high specific surface area, and tunable physicochemical properties, as well as their notable capacity for loading and sustained release of antimicrobial agents. Tailoring polymer or hybrid-based nanofibrous membranes with stimuli-responsive characteristics further enhances their versatility, enabling them to exhibit broad-spectrum or specific activity against diverse microorganisms. In this review, we elucidate the pivotal advancements achieved in the realm of stimuli-responsive antimicrobial electrospun nanofibers operating by light, temperature, pH, humidity, and electric field, among others. We provide a concise introduction to the strategies employed to design smart electrospun nanofibers with antimicrobial properties. The core section of our review spotlights recent progress in electrospun nanofiber-based systems triggered by single- and multi-stimuli. Within each stimulus category, we explore recent examples of nanofibers based on different polymers and antimicrobial agents. Finally, we delve into the constraints and future directions of stimuli-responsive nanofibrous materials, paving the way for their wider application spectrum and catalyzing progress toward industrial utilization. (AU) | |
| FAPESP's process: | 17/10582-8 - Production and characterization of graphene quantum dots and their application in chemical sensors |
| Grantee: | Murilo Henrique Moreira Facure |
| Support Opportunities: | Scholarships in Brazil - Doctorate |
| FAPESP's process: | 23/13428-0 - Conductive composite microneedles manufactured by 3D printing and applications in wearable biosensors |
| Grantee: | Kelcilene Bruna Teodoro Costa |
| Support Opportunities: | Scholarships in Brazil - Support Program for Fixating Young Doctors |
| FAPESP's process: | 17/20973-4 - Coaxial electrospun nanofibers based on chitosan for controlled release of antibiotics and periodontic lesion treatment |
| Grantee: | Danilo Martins dos Santos |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |
| FAPESP's process: | 23/01567-6 - Conductive composite microneedles manufactured by 3D printing and applications in wearable biosensors |
| Grantee: | Daniel Souza Corrêa |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 21/11738-7 - Multifunctional 3D-printed stimuli-responsive drug delivery system for periodontitis treatment |
| Grantee: | Danilo Martins dos Santos |
| Support Opportunities: | Scholarships abroad - Research Internship - Post-doctor |
| FAPESP's process: | 22/05316-5 - Development of functional polymeric biomaterials aimed at tissue regeneration and healing |
| Grantee: | Francisco Vieira dos Santos |
| Support Opportunities: | Scholarships in Brazil - Doctorate |
| FAPESP's process: | 18/22214-6 - Towards a convergence of technologies: from sensing and biosensing to information visualization and machine learning for data analysis in clinical diagnosis |
| Grantee: | Osvaldo Novais de Oliveira Junior |
| Support Opportunities: | Research Projects - Thematic Grants |